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Zinc(II) niflumato complex effects on MMP activity and gene expression in human endometrial cell lines
Endometriosis is a persistent inflammatory illness which more and more impacts younger girls underneath 35 years of age and results in subfertility even infertility. Evaluation of the cytotoxic impact of zinc(II) niflumato advanced with neocuproine ([Zn(neo)(nif)2] or Zn-Nif) on immortalized human endometriotic cell line (12Z) and on management immortalized human endometrial stromal cell line (hTERT) was carried out utilizing xCELLigence know-how for roughly 72 h following the remedy with Zn-Nif in addition to cell viability Trypan Blue Assay. 12Z cell line proliferated extra slowly in comparison with unaffected cells, whereas hTERT cells didn’t present related conduct after remedy.
The advanced in all probability reduces the impact of pro-inflammatory pathways as a result of impact of NSAID, whereas presence of zinc may scale back the extent of ROS and regulate ER2 ranges and MMP exercise. The noticed results and excessive selectivity for quickly proliferating cells with elevated inflammatory exercise recommend an excellent prognosis of profitable lower of endometriosis stage with this advanced.

Mineralized polyplexes for gene supply: Enchancment of transfection effectivity as a consequence of calcium incubation and never mineralization

Gene remedy is an rising discipline wherein nucleic acids are used to manage protein expression. The need of delivering nucleic acids to particular cell varieties and intracellular websites calls for the usage of extremely specialised gene carriers. As a provider modification method, mineralization has been efficiently used to change viral and non-viral carriers, offering new properties that in the end intention to extend the transfection effectivity. Nonetheless, for the particular case of polyplexes utilized in gene remedy, latest literature exhibits that interplay with calcium, a elementary step of mineralization, could be efficient to extend transfection effectivity, leaving an ambiguity about of the function of mineralization for this sort of gene carriers.
To reply this query and to disclose the properties chargeable for rising transfection effectivity, we mineralized poly(aspartic acid) coated polyplexes at various CaCl2 and Na3PO4 concentrations, and evaluated the resultant carriers for physicochemical and morphological traits, in addition to transfection and supply effectivity with MC3T3-E1 mouse osteoblastic cells.
We discovered that each mineralization and calcium incubation positively affected the transfection effectivity and uptake of polyplexes in MC3T3-E1 cells. Nonetheless, this impact originated from the properties achieved by polyplexes after the calcium incubation step which might be maintained after mineralization, together with particle measurement enhance, improved pDNA binding, and adjustment of zeta potential. Contemplating that mineralization generally is a longer course of than calcium incubation, we discover that calcium incubation could be enough and most popular if improved transfection effectivity in vitro is the one impact desired.
Staphylococcus epidermidis has been not too long ago acknowledged as an rising nosocomial pathogen. There are considerations over the rising virulence potential of this commensal as a result of capabilities of transferring cell genetic parts to Staphylococcus aureus by way of staphylococcal chromosomal cassette (SCCmec) and the carefully associated arginine catabolic cell factor (ACME) and the copper and mercury resistance island (COMER). The potential pathogenicity of S. epidermidis, significantly from blood stream infections, has been poorly investigated. On this research, 24 S. epidermidis remoted from blood stream infections from Oman had been investigated utilizing entire genome sequence evaluation. Core genome phylogenetic bushes revealed one third of the isolates belong to the multidrug resistance ST-2.
Genomic evaluation unraveled a typical incidence of SCCmec sort IV and ACME factor predominantly sort I organized in a composite island. The genetic composition of ACME was extremely variable amongst isolates of identical or totally different STs. The COMER-like island was absent in all of our isolates. Lowered copper susceptibility was noticed amongst isolates of ST-2 and ACME sort I, adopted by ACME sort V. In conclusion, on this work, we establish a prevalent incidence of extremely variable ACME parts in several hospital STs of S. epidermidis in Oman, thus strongly suggesting the speculation that ACME varieties developed from carefully associated STs.
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Antibiotics, Multidrug-Resistant Micro organism, and Antibiotic Resistance Genes: Indicators of Contamination in Mangroves?

Multidrug-resistant micro organism and antibiotic resistance genes will be monitored as indicators of contamination in a number of environments. Mangroves are among the many most efficient ecosystems, and though they are often resilient to the motion of local weather phenomena, their equilibrium will be affected by anthropogenic actions. Relating to the presence and persistence of multidrug-resistant micro organism in mangroves, it is not uncommon to suppose that this ecosystem can operate as a reservoir, which might disperse the antibiotic resistance capability to human pathogens, or function a filter to remove drug-resistant genes.
The attainable affect of anthropogenic actions carried out close to mangroves is reviewed, together with wastewater remedy, meals manufacturing techniques, leisure, and tourism. Hostile results of antibiotic resistance genes or multidrug-resistant micro organism, thought-about as rising contaminants, haven’t been reported but in mangroves. Quite the opposite, mangrove ecosystems generally is a pure technique to remove antibiotics, antibiotic-resistant micro organism, and even antibiotic-resistant genes from the surroundings.
Though mangroves’ function in reducing antibiotics and antibiotic resistance genes from the surroundings is being proposed, the mechanisms by which these vegetation scale back these rising contaminants haven’t been elucidated and want additional research. Moreover, additional analysis is required on the consequences of antibiotics and antibiotic-resistant micro organism in mangroves to generate an evaluation of the human contribution to the degradation of this particular ecosystem in addition to to outline if these contaminants can be utilized as indicators of contamination in mangrove ecosystems.
Irrigation water is effectively generally known as potential supply of pathogens in recent produce. Nonetheless, its function in transferring antibiotic resistance determinants is much less effectively investigated. Due to this fact, we analyzed the contribution of floor and faucet water to the resistome of overhead-irrigated chive vegetation. Area-grown chive was irrigated with both floor water (R-system) or faucet water (D-system), from planting to reap. Water alongside the 2 irrigation chains in addition to the respective vegetation had been repeatedly sampled and screened for 264 antibiotic resistance genes (ARGs) and cell genetic parts (MGEs), utilizing high-capacity qPCR.
Differentially plentiful (DA) ARGs had been decided by evaluating the 2 systems. On R-chive, β-lactam ARGs, multidrug-resistance (MDR) determinants, and MGEs had been most plentiful, whereas D-chive featured DA ARGs from the vancomycin class. Variety and variety of DA ARGs was the best on younger chives, strongly diminished at harvest, and elevated once more on the finish of shelf life.
Most ARGs extremely enriched on R- in comparison with D-chive had been additionally enriched in R- in comparison with D-sprinkler water, indicating that water performed a significant function in ARG enrichment. Of be aware, blaKPC was detected at excessive ranges in floor water and chive. We conclude that water high quality considerably impacts the resistome of the irrigated produce.
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Genetic Aberrations of DNA Repair Pathways in Prostate Cancer: Translation to the Clinic
Prostate most cancers (PC) is the second most typical most cancers in males worldwide. Because of the large-scale sequencing efforts, there may be presently a greater understanding of the genomic panorama of PC. The identification of defects in DNA restore genes has led to medical research that present a powerful rationale for growing poly (ADP-ribose) polymerase (PARP) inhibitors and DNA-damaging brokers on this molecularly outlined subset of sufferers.
The identification of molecularly outlined subgroups of sufferers has additionally different medical implications; for instance, we now know that carriers of breast most cancers 2 (BRCA2) pathogenic sequence variants (PSVs) have elevated ranges of serum prostate particular antigen (PSA) at analysis, elevated proportion of excessive Gleason tumors, elevated charges of nodal and distant metastases, and excessive recurrence fee; BRCA2 PSVs confer decrease general survival (OS). Distinct tumor PSV, methylation, and expression patterns have been recognized in BRCA2 in contrast with non-BRCA2 mutant prostate tumors.
A number of DNA injury response and restore (DDR)-targeting brokers are presently being evaluated both as single brokers or together in sufferers with PC. On this overview article, we spotlight the biology and medical implications of deleterious inherited or acquired DNA restore pathway aberrations in PC and provide an outline of recent brokers being developed for the remedy of PC.

Analyzing Plant Gene Focusing on Outcomes and Conversion Tracts with Nanopore Sequencing

The high-throughput molecular evaluation of gene concentrating on (GT) occasions is made technically difficult by the residual presetabce of donor molecules. Giant donor molecules prohibit primer placement, leading to lengthy amplicons that can’t be readily analyzed utilizing customary NGS pipelines or qPCR-based approaches resembling ddPCR. In crops, removing of extra donor is time and useful resource intensive, typically requiring plant regeneration and weeks to months of effort.
Right here, we utilized Oxford Nanopore Amplicon Sequencing (ONAS) to bypass the constraints imposed by donor molecules with 1 kb of homology to the goal and dissected GT outcomes at three loci in Nicotiana benthamia leaves. We developed a novel bioinformatic pipeline, Phased ANalysis of Genome Modifying Amplicons (PANGEA), to cut back the impact of ONAS error on amplicon evaluation and captured tens of 1000’s of somatic plant GT occasions.
Moreover, PANGEA allowed us to gather 1000’s of GT conversion tracts 5 days after reagent supply with no choice, revealing that almost all occasions utilized tracts lower than 100 bp in size when incorporating an 18 bp or three bp insertion. These knowledge reveal the usefulness of ONAS and PANGEA for plant GT evaluation and supply a mechanistic foundation for future plant GT optimization.

Genome Sequence Evaluation of the Fungal Pathogen Fusarium graminearum Utilizing Oxford Nanopore Know-how

Fusarium graminearum is a plant pathogen of world significance which causes not solely important yield loss but additionally crop spoilage as a consequence of mycotoxins that render grain unsafe for human or livestock consumption. Though the complete genome of a number of F. graminearum isolates from completely different elements of the world have been sequenced, there aren’t any comparable research of isolates originating from China.
The present research sought to deal with this by sequencing the F. graminearum isolate FG-12, which was remoted from the roots of maize seedlings exhibiting typical signs of blight rising within the Gansu province, China, utilizing Oxford Nanopore Know-how (ONT). The FG-12 isolate was discovered to have a 35.9 Mb genome comprised of 5 scaffolds comparable to the 4 chromosomes and mitochondrial DNA of the F. graminearum sort pressure, PH-1.
The genome was discovered to comprise an roughly 2.23% repetitive sequence and encode 12,470 predicted genes. Extra bioinformatic evaluation recognized 437 genes that had been predicted to be secreted effectors, certainly one of which was confirmed to set off a hypersensitive responses (HR) within the leaves of Nicotiana benthamiana throughout transient expression experiments using agro-infiltration. The F. graminearum FG-12 genome sequence and annotation knowledge produced within the present research present a particularly helpful useful resource for each intra- and inter-species comparative analyses in addition to for gene purposeful research, and will enormously advance our understanding of this essential plant pathogen.
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hicstatistics

Prevalence of Virulence Genes and Antimicrobial Resistance of E. coli O157:H7 Remoted from the Beef Carcass of Bahir Dar Metropolis, Ethiopia

Ecoli O157:H7 is among the most virulent foodborne pathogens. The purpose of this research was to isolate E. coli O157:H7, decide virulence genes carried by the organism, and assess the antimicrobial susceptibility sample of the isolates from beef carcass samples at Bahir Dar metropolis. Swab samples (n = 280) had been collected from the carcass of cattle slaughtered on the abattoir and processed utilizing sorbitol MacConkey agar supplemented with cefixime telluride and confirmed with latex agglutination take a look at.
A polymerase chain response was carried out on isolates for the detection of virulence genes stx1stx2hlyA, and eae. Antimicrobial susceptibility testing was carried out utilizing the disk diffusion technique. Of 280 samples processed, 25 (8.9%) isolates had been optimistic. Out of 25 isolates subjected for molecular detection, 8 (32%) and 14 (56%) isolates possessed stx1 and stx2 genes, respectively; from these, 5 (20%) isolates had each genes for the manufacturing of Shiga toxins.
In contrast from different virulent genes comparatively increased proportion of 18 (72%) isolates carried the hlyA gene. Solely 5 (2%) isolates had been optimistic for eae. Resistance was detected in all 25 (100%) isolates and three (12%) towards clindamycin and trimethoprim, respectively. This research end result highlights the potential risk to public well being. The abattoir staff should be conscious concerning the pathogen and may comply with applicable practices to stop contamination of meat supposed for human consumption.

Genome-scale RNAi screens in African trypanosomes

Genome-scale genetic screens enable researchers to quickly establish the genes and proteins that influence a specific phenotype of curiosity. In African trypanosomes, RNA interference (RNAi) knockdown screens have revealed mechanisms underpinning drug resistance, drug transport, prodrug metabolism, quorum sensing, genome replication, and gene expression management.
RNAi screening has additionally been remarkably efficient at highlighting promising potential antitrypanosomal drug targets. The primary ever RNAi library display was applied in African trypanosomes, and genome-scale RNAi screens and different associated approaches proceed to have a serious influence on trypanosomatid analysis. Right here, I overview these impacts when it comes to each discovery and translation.
The latest software of macroecological instruments and ideas has made it potential to establish constant patterns within the distribution of microbial biodiversity, which enormously improved our understanding of the microbial world at massive scales. Nevertheless, the distribution of microbial capabilities stays largely uncharted from the macroecological perspective. Right here, we used macroecological fashions to look at how the genes encoding the purposeful capabilities of microorganisms are distributed inside and throughout soil methods.
Fashions constructed utilizing purposeful gene array knowledge from 818 soil microbial communities confirmed that the occupancy-frequency distributions of genes had been bimodal in each studied website, and that their rank-abundance distributions had been finest described by a lognormal mannequin. As well as, the relationships between gene occupancy and abundance had been optimistic in all websites.
This allowed us to establish genes with excessive abundance and ubiquitous distribution (core) and genes with low abundance and restricted spatial distribution (satellites), and to indicate that they encode completely different units of microbial traits. Widespread genes encode microbial traits associated to the primary biogeochemical cycles (C, N, P and S) whereas uncommon genes encode traits associated to adaptation to environmental stresses, resembling nutrient limitation, resistance to heavy metals and degradation of xenobiotics.
Total, this research characterised for the primary time the distribution of microbial purposeful genes inside soil methods, and spotlight the curiosity of macroecological fashions for understanding the purposeful group of microbial methods throughout spatial scales.
hicstatistics
The Genetic Diversification of a Single Bluetongue Virus Strain Using an In Vitro Model of Alternating-Host Transmission

Bluetongue virus (BTV) is an arbovirus that has been related to dramatic epizootics in each wild and residential ruminants in latest a really very long time. As a segmented, double-stranded RNA virus, BTV can evolve by a number of mechanisms because of its genomic constructing. Nonetheless, the have an effect on of BTV’s alternating-host transmission cycle on the virus’s genetic diversification stays poorly understood. Full genome sequencing approaches present a platform for investigating the have an effect on of host-alternation all by all ten segments of BTV’s genome.

 

To grasp the function of alternating hosts in BTV’s genetic diversification, a subject isolate was passaged beneath three totally completely completely different situations: (i) serial passages in Culicoidessonorensis cells, (ii) serial passages in bovine pulmonary artery endothelial cells, or (iii) alternating passages between insect and bovine cells.

 

Aliquots of virus had been sequenced, and single nucleotide variants had been acknowledged. Measures of viral inhabitants genetics had been used to quantify the genetic diversification that occurred. Two consensus variants in segments 5 and 10 occurred in virus from all three situations.

 

Whereas variants arose all by all passages, measures of genetic differ remained largely comparable all by cell customized situations. Irrespective of passage in a relaxed in vitro system, we discovered that this BTV isolate exhibited genetic stability all by passages and situations. Our findings underscore the expensive function that full genome sequencing could play in enhancing understanding of viral evolution and spotlight the genetic stability of BTV.

Novel Gene Rearrangement and the Full Mitochondrial Genome of Cynoglossusmonopus: Insights into the Envolution of the Household Cynoglossidae (Pleuronectiformes)

 

Cynoglossusmonopus, a small benthic fish, belongs to the Cynoglossidae, Pleuronectiformes. It was not normally studied because of its low abundance and cryptical life-style. With the intention to know the mitochondrial genome and the phylogeny in Cynoglossidae, all of the mitogenome of C. monopus has been sequenced and analyzed for the primary time. The entire dimension is 16,425 bp, usually containing 37 genes with novel gene rearrangements. The tRNA-Gln gene is inverted from the sunshine to the heavy strand and translocated from the downstream of tRNA-Ile gene to its upstream. The administration area (CR) translocated downstream to the three’-end of ND1 gene adjoining to inverted to tRNA-Gln and left a 24 bp hint fragment inside the real place.

 

 

The phylogenetic timber had been reconstructed by Bayesian inference (BI) and most likelihood (ML) strategies based completely on the mitogenomic data of 32 tonguefish species and two outgroups. The outcomes help the concept Cynoglossidae is a monophyletic group and degree out that C. monopus has the closest phylogenetic relationship with C. puncticeps.

 

By combining fossil data and mitogenome data, the time-calibrated evolutionary tree of households Cynoglossidae and Soleidae was firstly supplied, and it was indicated that Cynoglossidae and Soleidae had been differentiated from one another all by Paleogene, and the evolutionary technique of household Cynoglossidae coated the Quaternary, Neogene and Paleogene durations.

 

Genome-Broad Identification and Characterization of the SHI-Associated Sequence Gene Household in Rice

 

Rice (Oryzasativa) yield is correlated to varied elements. Transcription regulators are necessary elements, akin to the frequently SHORT INTERNODES-related sequences (SRSs), which encode proteins with single zinc finger motifs. Nonetheless, data relating to the evolutionary and smart traits of the SRS gene household members in rice is inadequate.

 

Subsequently, we carried out a genome-wide screening and characterization of the OsSRS gene household in Oryzasativa japonica rice. We furthermore examined the SRS proteins from 11 rice sub-species, consisting of three cultivars, 6 wild varieties, and some completely completely different genome sorts. SRS members from maize, sorghum, Brachypodiumdistachyon, and Arabidopsis had been furthermore investigated.

 

All these SRS proteins exhibited species-specific traits, together with monocot- and dicot-specific traits, as assessed by phylogenetic evaluation, which was additional validated by gene constructing and motif analyses. Genome comparisons revealed that segmental duplications may have carried out crucial roles contained in the recombination of the OsSRS gene household and their expression ranges. The household was primarily subjected to purifying selective stress.

 

Along with, the expression data demonstrated the distinct responses of OsSRS genes to varied abiotic stresses and hormonal cures, indicating their smart divergence. Our research gives an exquisite reference for elucidating the choices of SRS genes in rice.

 

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hicstatistics

Ginsenoside Rg1 improves pathological damages by activating the p21‑p53‑STK pathway in ovary and Bax‑Bcl2 within the uterus in untimely ovarian insufficiency mouse fashions

The intention of the current research was to research the results of the ginsenoside Rg1 on D‑galactose (D‑gal)‑induced mouse fashions of untimely ovarian insufficiency (POI) and the associated mechanisms. C57BL/6 feminine mice had been randomly grouped into the next: i) D‑gal [subcutaneously (s.c.) 200 mg/kg/d D‑gal for 42 days]; ii) Rg1 [intraperitoneally (i.p.) 20 mg/kg/d Rg1 for 28 days]; iii) D‑gal + Rg1 (s.c. 200 mg/kg/d D‑gal for 42 days adopted by i.p. 20 mg/kg/d Rg1 for 28 days); and iv) saline teams (equal quantity of saline s.c. and that i.p.). Hematoxylin and eosin staining and electron microscopy had been used to research uterine and ovarian morphology.
Expression ranges of senescence components (p21, p53 and serine/threonine kinase), secretion of professional‑inflammatory cytokines [interleukin (IL)‑6, tumor necrosis factor (TNF)‑α and IL‑1β] and the actions of oxidation biomarkers [superoxide dismutase (T‑SOD), malondialdehyde (MDA) and glutathione peroxidase (GSH‑px)] had been analyzed. The outcomes confirmed that mice within the Rg1 + D‑gal group had considerably larger uterine and ovarian weight in contrast with these within the D‑gal group.
Uterus morphology was additionally improved, primarily based on the comparability between the D‑gal group and the Rg1 + D‑gal group. As well as, the Rg1 remedy after D‑gal administration considerably decreased the expression of senescence‑related components, enhanced the actions of anti‑oxidant enzymes complete T‑SOD and GSH‑px along with decreasing TNF‑α, IL‑1β, MDA and IL‑6 (primarily based on the comparability between the D‑gal group and the Rg1 + D‑gal group).
In conclusion, the current research advised that the ginsenoside Rg1 improved pathological damages within the ovary and uterus by rising anti‑oxidant and anti‑inflammatory talents while decreasing the expression of senescence signaling pathways in POI mouse fashions.

 

 

PP1 (Src kinase inhibitor)

SIH-469-25MG 25 mg
EUR 619
  • PP1 is a potent and selective Src family protein tyrosine kinase inhibitor. This has a range of effects and implications. Structural studies have revealed that PP1 binds to the ATP-binding site in tyrosine kinases and Ser/Thr kinases. PP1 displays >
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Description: The substance PP1 is a src kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in DMSO (25 mg/ml), slightly soluble in 100% ethanol.

PP1 (Src kinase inhibitor)

SIH-469-5MG 5 mg
EUR 205
  • PP1 is a potent and selective Src family protein tyrosine kinase inhibitor. This has a range of effects and implications. Structural studies have revealed that PP1 binds to the ATP-binding site in tyrosine kinases and Ser/Thr kinases. PP1 displays >
  • Show more
Description: The substance PP1 is a src kinase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in DMSO (25 mg/ml), slightly soluble in 100% ethanol.

PP2 (Src kinase inhibitor)

SIH-470-25MG 25 mg
EUR 737
  • PP2 is a selective inhibitor of Src-family tyrosine kinases. PP2 has been shown to inhibit Lck, FynT, and phosphorylation of focal adhesion kinase (FAK) and potently inhibits Hck, Lck (p56) and Fyn (p59). PP2 displays > 10000-fold selectivity over ZA
  • Show more
Description: The substance PP2 is a src kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is off-white solid which is soluble in DMSO (25 mg/ml).

PP2 (Src kinase inhibitor)

SIH-470-5MG 5 mg
EUR 233
  • PP2 is a selective inhibitor of Src-family tyrosine kinases. PP2 has been shown to inhibit Lck, FynT, and phosphorylation of focal adhesion kinase (FAK) and potently inhibits Hck, Lck (p56) and Fyn (p59). PP2 displays > 10000-fold selectivity over ZA
  • Show more
Description: The substance PP2 is a src kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is off-white solid which is soluble in DMSO (25 mg/ml).

SRC kinase signaling inhibitor 1 (SRCIN1) Antibody

abx331175-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

SRC kinase signaling inhibitor 1 (SRCIN1) Antibody

20-abx327632
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

HPGDS inhibitor 1

B1046-1 1 mg
EUR 181
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation.

Anti-Src Rabbit Monoclonal Antibody

M00107-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Src Antibody. Validated in IF, WB and tested in Human, Rat.

Human SRC kinase signaling inhibitor 1, SRCIN1 ELISA KIT

ELI-13954h 96 Tests
EUR 824

Mouse SRC kinase signaling inhibitor 1, Srcin1 ELISA KIT

ELI-18126m 96 Tests
EUR 865

Rat SRC kinase signaling inhibitor 1 (SRCIN1) ELISA Kit

abx392007-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Human SRC kinase signaling inhibitor 1 (SRCIN1) ELISA Kit

abx385443-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Mouse SRC kinase signaling inhibitor 1 (SRCIN1) ELISA Kit

abx390644-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

pp60 c-src (521-533) (phosphorylated)

B5235-1 1 mg
EUR 266

SRC 1 Antibody

abx238217-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

187-1, N-WASP inhibitor

B5251-1 1 mg
EUR 399

Srcin1 ELISA Kit| Mouse SRC kinase signaling inhibitor 1 ELISA

EF016287 96 Tests
EUR 689

YAP-TEAD Inhibitor 1 (Peptide 17)

A1149-1 1 mg
EUR 235

SRC - 1 (682–697)

5-01959 4 x 1mg Ask for price

SRC-1 (pT1179) Antibody

abx217070-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.

anti- SRC 1 antibody

FNab08217 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:5000IHC: 1:20-1:200
  • Immunogen: nuclear receptor coactivator 1
  • Uniprot ID: Q15788
  • Gene ID: 8648
  • Research Area: Signal Transduction, Metabolism
Description: Antibody raised against SRC 1

T338C Src-IN-1

HY-16905 100mg
EUR 2943

Anti-SRC 1 antibody

PAab08217 100 ug
EUR 386

Srcin1 ELISA Kit| Rat SRC kinase signaling inhibitor 1 ELISA Ki

EF019367 96 Tests
EUR 689

Chk2 Inhibitor

1702-1
EUR 180

SCD1 Inhibitor

1716-1
EUR 218

ACC2 Inhibitor

1717-1
EUR 218

Syk Inhibitor

1983-1
EUR 126

Stat5 Inhibitor

9484-1
EUR 120

EGFR Inhibitor

C3327-1 1 mg
EUR 154
Description: EGFR inhibitor is a cell permeable, pyrimidine compound that selectively inhibits the EGFR kinase with IC50 value of 21 nM [1]. EGFR is a transmembrane protein, and is a receptor for members of epidermal growth factor family.

Lck Inhibitor

A3539-1 1 mg
EUR 154
Description: Lck Inhibitor is a small-molecule inhibitor of with IC50 value of 7 nM [1].The lymphocyte specific kinase which expressed in NK cells and T-cells is a member of the Src kinase family.

NFAT Inhibitor

A4539-1 1 mg
EUR 138
Description: Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells.

c-SRC (c-SRC) Antibody

20-abx007517
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

c-SRC (c-SRC) Antibody

20-abx008688
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Src/ Rat Src ELISA Kit

ELI-18125r 96 Tests
EUR 886

c-SRC (c-SRC) Antibody

abx232027-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

c-SRC (c-SRC) Antibody

abx232028-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Phosphatase Inhibitor Cocktail 1 (100X in DMSO)

K1012-1 1 ml
EUR 102

NCOA1/SRC-1/KAT13A/ Rat NCOA1/ SRC- 1/ KAT13A ELISA Kit

ELA-E11292r 96 Tests
EUR 886

Human Plasminogen Activator Inhibitor-1 (PAI-1) AssayMax ELISA Kit

EP1100-1 96 Well Plate
EUR 417

SERPINE1 Plasminogen Activator Inhibitor-1 Human Recombinant Protein

PROTP05121-1 Regular: 25ug
EUR 317
Description: SERPINE1 Human Recombinant fused to N-terminal His-Tag produced in E.Coli is a single, non-glycosylated polypeptide chain containing 400 amino acids (24-402) and having a molecular mass of 45 kDa.;The SERPINE1 is purified by proprietary chromatographic techniques.

Bromodomain Inhibitor, (+)-JQ1

2070-1
EUR 164

Smad3 Inhibitor, SIS3

2227-1
EUR 164

CFTR Inhibitor-172

2487-1
EUR 120

EZSolution? SCD1 Inhibitor

2548-1
EUR 207

FAS Inhibitor, C75

1547-1
EUR 180

Batimastat (MMP Inhibitor)

1704-1
EUR 180

Cathepsin G Inhibitor

1982-1
EUR 240

USP7/USP47 Inhibitor

B2538-1
EUR 142

Cdk9 Inhibitor II

B2903-1
EUR 142

MLCK inhibitor peptide

B5236-1 1 mg
EUR 184

Rac1 Inhibitor W56

B5274-1 1 mg
EUR 399

Lyn peptide inhibitor

B5285-1 1 mg
EUR 601

Calpain Inhibitor XII

C5347-1 1 mg
EUR 145
Description: Ki: 19 nM for ?-calpain Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I.Calpain is a protein belonging to the family of calcium-dependent, non-lysosomal cysteine proteases expressed ubiquitously in mammals and many other organisms.

MMP-13 Inhibitor

C4331-1 1 mg
EUR 187
Description: IC50: 8 nMMMP-13 Inhibitor is a MMP-13 inhibitor.Matrix metalloproteinases (MMPs), a family of zinc endopeptidases, can degrade proteins of the extracellular matrix, such as collagens, elastins, matrix glycoproteins, and proteoclycans.

EGFR/ErbB2 Inhibitor

C3285-1 1 mg
EUR 186
Description: IC50: 20 and 79 nM for EGFR and c-ErbB2, respectivelyEGFR/ErbB2 Inhibitor is an EGFR and c-ErbB2 inhibitor.EGFR and c-ErbB-2 are members of the epidermal growth factor receptor subfamily of protein tyrosine kinases.

MMP Inhibitor II

C4081-1 1 mg
EUR 119
Description: MMP Inhibitor II is a potent, reversible and broad-range inhibitor of matrix metalloproteinases (MMPs) with IC50 values of 24 nM, 18.4 nM, 30 nM and 2.7 nM for MMP-1, MMP-3, MMP-7 and MMP-9, respectively [1].

MEK Inhibitor Set

A9907-1 1 Set
EUR 224

Bromodomain Inhibitor, (+)-JQ1

A1910-1 1 mg
EUR 108
Description: Bromodomain Inhibitor, (+)-JQ1 is a potent and highly specific inhibitor for the BET (bromodomain and extra-terminal) family of bromodomains. (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively.

DiscoveryProbe? Inhibitor Library

L1048-.1 100 uL/well(10 mM solution)
EUR 14387

Plasminogen Activator Inhibitor 1 (PAI-1), hexapeptide, Human

SP-55196-1 0.5 mg
EUR 141

Src antibody

20R-2005 50 ug
EUR 281
Description: Rabbit polyclonal Src antibody

Src antibody

20R-2336 50 ug
EUR 281
Description: Rabbit polyclonal Src antibody

SRC antibody

70R-20514 50 ul
EUR 435
Description: Rabbit polyclonal SRC antibody

Src antibody

70R-13956 100 ug
EUR 322
Description: Affinity purified Rabbit polyclonal Src antibody

SRC Antibody

48186-100ul 100ul
EUR 333

SRC Antibody

48186-50ul 50ul
EUR 239

SRC Antibody

35933-100ul 100ul
EUR 252

SRC antibody

10R-2138 100 ul
EUR 457
Description: Mouse monoclonal SRC antibody

SRC antibody

10R-2154 100 ul
EUR 435
Description: Mouse monoclonal SRC antibody

Src antibody

10R-8485 100 ul
EUR 393
Description: Mouse monoclonal Src antibody

RR-SRC

5-01886 4 x 5mg Ask for price

Src Antibody

48902-100ul 100ul
EUR 333

Src Antibody

48902-50ul 50ul
EUR 239

Src Antibody

49317-100ul 100ul
EUR 333

Src Antibody

49317-50ul 50ul
EUR 239

SRC Antibody

1-CSB-PA001803
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against SRC. Recognizes SRC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000

SRC Antibody

1-CSB-PA001806
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against SRC. Recognizes SRC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

SRC Antibody

1-CSB-PA001807
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against SRC. Recognizes SRC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000

SRC Antibody

1-CSB-PA001809
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against SRC. Recognizes SRC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000

SRC Antibody

1-CSB-PA050134
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against SRC. Recognizes SRC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

SRC Antibody

1-CSB-PA080378
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against SRC. Recognizes SRC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

SRC Antibody

1-CSB-PA081645
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against SRC. Recognizes SRC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50

src Antibody

1-CSB-PA24479A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against src. Recognizes src from Zebrafish. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:5000

Src antibody

70R-37554 100 ug
EUR 273
Description: Rabbit Polyclonal Src antibody

Src antibody

70R-37603 100 ug
EUR 273
Description: Rabbit Polyclonal Src antibody

Src antibody

70R-32504 100 ug
EUR 327
Description: Rabbit polyclonal Src antibody

Src antibody

70R-32507 100 ug
EUR 327
Description: Rabbit polyclonal Src antibody

Src antibody

70R-32737 100 ug
EUR 327
Description: Rabbit polyclonal Src antibody

Src antibody

70R-34409 100 ug
EUR 327
Description: Rabbit polyclonal Src antibody
hicstatistics
Melting dsDNA Donor Molecules Vastly Improves Precision Genome Enhancing in Caenorhabditiselegans

CRISPR genome modifying has revolutionized genetics in quite a few organisms. Contained in the nematode Caenorhabditiselegans one injection into every of the 2 gonad arms of an grownup hermaphrodite exposes tons of of meiotic germ cells to modifying mixtures, allowing the restoration of a variety of indels or small precision edits from every successfully injected animal. Sadly, significantly for extended insertions, modifying efficiencies can differ broadly, necessitating a variety of injections, and customarily requiring co-selection methods.

 

Correct proper right here we present that melting double stranded DNA (dsDNA) donor molecules earlier to injection will enhance the frequency of tangible homology-directed restore (HDR) by a variety of fold for longer edits. We describe troubleshooting methods that let persistently excessive modifying efficiencies ensuing, as an illustration, in as rather a lot as 100 unbiased GFP knock-ins from a single injected animal. These efficiencies make C. elegans by far the perfect metazoan to genome edit, eradicating limitations to the use and adoption of this facile system as a mannequin for understanding animal biology.

 

Water-Pipe Smoking Publicity Deregulates a Set of Genes Related to Human Head and Neck Most cancers Improvement and Prognosis

  • Water-pipe smoking (WPS) is popping into in all probability probably the most well-liked kind of tobacco use among the many many many youth, notably contained in the Coronary heart East, altering cigarettes quickly and turning into a crucial danger of tobacco dependancy worldwide. Smoke from WPS accommodates comparable toxins as these current in cigarette smoke and is linked instantly with plenty of sorts of cancers together with lung and head and neck (HN) carcinomas.

 

  • Nonetheless, the underlying molecular pathways and/or goal genes accountable for the carcinogenic course of are nonetheless unknown. On this research, human widespread oral epithelial (HNOE) cells, NanoStringPanCancer Pathways panel of 770 gene transcripts and quantitative real-time polymerase chain response (qRT-PCR) evaluation had been utilized to hunt out differentially expressed genes (DEG) modulated by WPS. In silico evaluation was carried out to analysis the have an effect on of those genes in HN most cancers affected specific particular person’s biology and consequence. We discovered that WPS can induce the epithelial-mesenchymal transition (EMT: hallmark of most cancers development) of HNOE cells.

 

  • Additional considerably, our evaluation of NanoString revealed 23 genes deregulated beneath the have an effect on of WPS, accountable for the modulation of cell cycle, proliferation, migration/invasion, apoptosis, sign transduction, and inflammatory response. Further evaluation was carried out utilizing qRT-PCR of HNOE WPS-exposed and unexposed cells supported the reliability of our NanoString data.

 

  • Furthermore, we exhibit these DEG to be upregulated in most cancers in distinction with widespread tissue. Utilizing the Kaplan-Meier evaluation, we seen a major affiliation between WPS-deregulated genes and relapse-free survival/full survival in HN most cancers victims. Our findings level out that WPS can modulate EMT together with a set of genes which may very well be instantly concerned in human HN carcinogenesis, thereby affecting HN most cancers victims’ survival.
hicstatistics
hicstatistics

A pilot research on the genetic differ of Mycobacterium tuberculosis troublesome strains from tuberculosis victims contained in the Littoral area of Cameroon

Background: The re-emergence of tuberculosis (TB) worldwide, compounded by multi-drug resistance (MDR) of the causative brokers constitutes a major concern to the administration of the illness. Speedy analysis and correct stress identification are pivotal to the administration of the illness. This pilot research investigated the genetic differ of Mycobacterium tuberculosis troublesome (MTBC) strains from TB victims contained in the Littoral area of Cameroon together with their resistance to rifampicin (RIF).

 

Victims and strategies: This was a cross sectional hospital-based research carried out between January and December 2017 and together with 158 isolates from sputum smear constructive people [105 (66.5%) males and 53 (33.5%) females]. Sputum samples had been examined utilizing Xpert MTB/RIF, adopted by customized on Lowenstein-Jensen medium. Isolates had been additional subjected to molecular characterization utilizing IS6110 typing, deletion evaluation and spoligotyping.

 

Outcomes: 13 (8.8%) of the 147 isolates with susceptibility outcomes accessible had been proof in direction of RIF. Drug resistance occurred in 5/50 (10%) feminine in contrast with 8/97 (8.2%) male (OR, 0.81; 0.25-2.62; p = 0.764), and there was no essential distinction all by means of the age ranges (p = 0.448). Nonetheless, RIF resistance was related (OR, 0.18, 95%CI, 0.05-0.69; p = 0.023) with beforehand handled victims [(4/14 (28.6%)] in contrast with new ones [9/133 (6.8%)].

The 150 acknowledged lineages included amongst others 54 (36%) Cameroon, 18 (12%) UgandaI, 32 (21.3%) Haarlem, 17 (11.3%) Ghana, 9(6%) West African 1, 7(4.7%) Delhi/CAS, 4 (2.7%) LAM and three (2%) UgandaII. Of the 150 isolates, a really highly effective cluster was the Cameroon SIT 61, with 43(28.7%) isolates. Six (35.3%) of the 17 UgandaI sub-lineage had been RIF resistant (OR, 9.58; 95%CI, 2.74-33.55, p = 0.001).

 

Conclusion: The cosmopolitan Littoral area presents with a giant Mycobacterium tuberculosis (MTB) strains differ and the UgandaI sub-lineage attainable related to RIF resistance. Understanding the unfold of this clade by the use of surveillance will improve TB administration contained in the area.

 

Human Pim-1 Oncogene (PIM1) ELISA Kit
DLR-PIM1-Hu-96T 96T
EUR 673
  • Should the Human Pim-1 Oncogene (PIM1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Pim-1 Oncogene (PIM1) ELISA Kit
DLR-PIM1-Ra-48T 48T
EUR 549
  • Should the Rat Pim-1 Oncogene (PIM1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Pim-1 Oncogene (PIM1) ELISA Kit
DLR-PIM1-Ra-96T 96T
EUR 718
  • Should the Rat Pim-1 Oncogene (PIM1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Hu-48Tests 48 Tests
EUR 544
Human Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Hu-96Tests 96 Tests
EUR 756
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Ra-48Tests 48 Tests
EUR 583
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Ra-96Tests 96 Tests
EUR 811
Human Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Hu-48Tests 48 Tests
EUR 521
Human Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Hu-96Tests 96 Tests
EUR 723
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Ra-48Tests 48 Tests
EUR 557
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Ra-96Tests 96 Tests
EUR 775
Pim-1 Oncogene (PIM1) Antibody
20-abx101233
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Pim-1 Oncogene (PIM1) Antibody
20-abx101234
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Pim-1 Oncogene (PIM1) Antibody
20-abx101235
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Pim-1 Oncogene (PIM1) Antibody
abx146417-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.
Pim-1 Oncogene (PIM1) Antibody
20-abx174066
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse)
4-PAC578Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1)
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat)
4-PAC578Ra01
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1)
Recombinant Pim-1 Oncogene (PIM1)
4-RPC578Hu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P11309
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 47.8kDa
  • Isoelectric Point: 5.8
Description: Recombinant Human Pim-1 Oncogene expressed in: E.coli
Recombinant Pim-1 Oncogene (PIM1)
4-RPC578Mu01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P06803
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 17.1kDa
  • Isoelectric Point: 5.6
Description: Recombinant Mouse Pim-1 Oncogene expressed in: E.coli
Recombinant Pim-1 Oncogene (PIM1)
4-RPC578Ra01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P26794
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 17.4kDa
  • Isoelectric Point: Inquire
Description: Recombinant Rat Pim-1 Oncogene expressed in: E.coli
Pim-1 Oncogene (PIM1) Antibody (Biotin)
20-abx271779
  • EUR 453.00
  • EUR 244.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Pim-1 Oncogene (PIM1) Antibody (Biotin)
20-abx272590
  • EUR 467.00
  • EUR 244.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Pim-1 Oncogene (PIM1) Antibody (Biotin)
20-abx273089
  • EUR 481.00
  • EUR 244.00
  • EUR 1414.00
  • EUR 662.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), APC
4-PAC578Mu01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Biotinylated
4-PAC578Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Cy3
4-PAC578Mu01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), FITC
4-PAC578Mu01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), HRP
4-PAC578Mu01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), PE
4-PAC578Mu01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), APC
4-PAC578Ra01-APC
  • EUR 364.00
  • EUR 3545.00
  • EUR 980.00
  • EUR 467.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Biotinylated
4-PAC578Ra01-Biotin
  • EUR 325.00
  • EUR 2658.00
  • EUR 777.00
  • EUR 400.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Cy3
4-PAC578Ra01-Cy3
  • EUR 444.00
  • EUR 4685.00
  • EUR 1265.00
  • EUR 581.00
  • EUR 261.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), FITC
4-PAC578Ra01-FITC
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), HRP
4-PAC578Ra01-HRP
  • EUR 332.00
  • EUR 3089.00
  • EUR 866.00
  • EUR 421.00
  • EUR 213.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), PE
4-PAC578Ra01-PE
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
Human Pim-1 Oncogene (PIM1) Protein
20-abx068546
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Rat Pim-1 Oncogene (PIM1) Protein
20-abx068547
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Mouse Pim-1 Oncogene (PIM1) Protein
20-abx068548
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat)
4-PAC578Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1)
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), APC-Cy7
4-PAC578Mu01-APC-Cy7
  • EUR 583.00
  • EUR 6610.00
  • EUR 1750.00
  • EUR 778.00
  • EUR 324.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), APC-Cy7
4-PAC578Ra01-APC-Cy7
  • EUR 608.00
  • EUR 6970.00
  • EUR 1840.00
  • EUR 814.00
  • EUR 335.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
Human Pim-1 Oncogene (PIM1)ELISA Kit
201-12-2345 96 tests
EUR 440
  • This Pim-1 Oncogene ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Human Pim-1 Oncogene (PIM1) CLIA Kit
20-abx190030
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Pim-1 Oncogene (PIM1) ELISA Kit
20-abx152744
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Pim-1 Oncogene (PIM1) ELISA Kit
abx573560-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.
Cow Pim-1 Oncogene (PIM1) ELISA Kit
abx519080-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.
Mouse Pim-1 Oncogene (PIM1) ELISA Kit
abx519082-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.
Rat Pim-1 Oncogene (PIM1) ELISA Kit
abx519083-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.
Human Pim-1 Oncogene(PIM1)ELISA Kit
QY-E04698 96T
EUR 361
Rat Pim-1 Oncogene(PIM1)ELISA Kit
QY-E10539 96T
EUR 400
Human Pim-1 Oncogene ELISA Kit (PIM1)
RK02083 96 Tests
EUR 521
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) CLIA Kit
4-SCC578Hu
  • EUR 5698.00
  • EUR 3061.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Pim-1 Oncogene Clia kit. Alternative names of the recognized antigen: Proto-Oncogene Serine/Threonine-Protein Kinase Pim-1
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1)Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
4-SEC578Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Pim-1 Oncogene elisa. Alternative names of the recognized antigen: Proto-Oncogene Serine/Threonine-Protein Kinase Pim-1
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Mouse Pim-1 Oncogene(PIM1)ELISA Kit
QY-E21184 96T
EUR 361
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), APC
4-PAC578Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), Biotinylated
4-PAC578Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), Cy3
4-PAC578Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), FITC
4-PAC578Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), HRP
4-PAC578Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), PE
4-PAC578Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
ELISA kit for Human PIM1 (Pim-1 Oncogene)
ELK3785 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pim-1 Oncogene (PIM1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Pim-1 Oncoge
  • Show more
Description: A sandwich ELISA kit for detection of Pim-1 Oncogene from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), APC-Cy7
4-PAC578Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
Polyclonal PIM1 / Pim-1 Antibody (aa24-37)
APG01139G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PIM1 / Pim-1 (aa24-37). This antibody is tested and proven to work in the following applications:
Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349
Rabbit Pim 1 Oncogene ELISA kit
E04P0753-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Pim 1 Oncogene ELISA kit
E04P0753-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Pim 1 Oncogene ELISA kit
E04P0753-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Proto-oncogene serine/threonine-protein kinase pim-1(PIM1) ELISA kit
CSB-E11825h-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Proto-oncogene serine/threonine-protein kinase pim-1 (PIM1) in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human Proto-oncogene serine/threonine-protein kinase pim-1(PIM1) ELISA kit
1-CSB-E11825h
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Proto-oncogene serine/threonine-protein kinase pim-1(PIM1) in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx214602
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx125380
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
abx033772-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
abx033772-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx241258
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx327418
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx302380
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280
Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human)
4-PAN637Hu01
  • EUR 262.00
  • EUR 2747.00
  • EUR 679.00
  • EUR 331.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3)
Pim-2 Oncogene (PIM2) Polyclonal Antibody (Human)
4-PAP797Hu01
  • EUR 262.00
  • EUR 2747.00
  • EUR 679.00
  • EUR 331.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Leu82~Glu291)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-2 Oncogene (PIM2)
Pim-2 Oncogene (PIM2) Polyclonal Antibody (Mouse)
4-PAP797Mu01
  • EUR 266.00
  • EUR 2813.00
  • EUR 694.00
  • EUR 337.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Gly98~Cys319)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-2 Oncogene (PIM2)
Pim-2 Oncogene (PIM2) Polyclonal Antibody (Rat)
4-PAP797Ra01
  • EUR 275.00
  • EUR 2958.00
  • EUR 727.00
  • EUR 350.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Leu34~Glu292)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-2 Oncogene (PIM2)
hicstatistics
Novel Gene Rearrangement and the Full Mitochondrial Genome of Cynoglossusmonopus: Insights into the Envolution of the Family Cynoglossidae (Pleuronectiformes)

Cynoglossusmonopus, a small benthic fish, belongs to the Cynoglossidae, Pleuronectiformes. It was not usually studied due to its low abundance and cryptical life-style. With the intention to understand the mitochondrial genome and the phylogeny in Cynoglossidae, all the mitogenome of C. monopus has been sequenced and analyzed for the first time. The whole dimension is 16,425 bp, generally containing 37 genes with novel gene rearrangements.

 

The tRNA-Gln gene is inverted from the sunshine to the heavy strand and translocated from the downstream of tRNA-Ile gene to its upstream. The administration space (CR) translocated downstream to the three’-end of ND1 gene adjoining to inverted to tRNA-Gln and left a 24 bptrace fragment inside the genuine place.

 

The phylogenetic timber had been reconstructed by Bayesian inference (BI) and most probability (ML) methods based mostly totally on the mitogenomic info of 32 tonguefish species and two outgroups. The outcomes assist the idea that Cynoglossidae is a monophyletic group and level out that C. monopus has the closest phylogenetic relationship with C. puncticeps.

 

By combining fossil info and mitogenome info, the time-calibrated evolutionary tree of households Cynoglossidae and Soleidae was firstly provided, and it was indicated that Cynoglossidae and Soleidae had been differentiated from each other all through Paleogene, and the evolutionary strategy of family Cynoglossidae coated the Quaternary, Neogene and Paleogene durations.

 

 

The Full Chloroplast Genome of Arabidopsis thaliana Isolated in Korea (Brassicaceae): An Investigation of Intraspecific Variations of the Chloroplast Genome of Korean A. thaliana

 

 

Arabidopsis thaliana (L.) Heynh. is a model organism of plant molecular biology. Higher than 1,700 full genome sequences have been sequenced, nonetheless no Korean isolate genomes have been sequenced to this point though many A. thaliana isolated in Japan and China have been sequenced. To understand the genetic background of Korean pure A. thaliana (named as 180404IB4),

 

we provided its full chloroplast genome, which is 154,464 bp prolonged and has Four subregions: 85,164 bp of giant single copy (LSC) and 17,781 bp of small single copy (SSC) areas are separated by 26,257 bp of inverted repeat (IRs) areas along with 130 genes (85 protein-coding genes, eight rRNAs, and 37 tRNAs). Fifty single nucleotide polymorphisms (SNPs) and 14 insertion and deletions (INDELs) are acknowledged between 180404IB4 and Col0.

 

In addition to, 101 SSRs and 42 extendedSSRs had been acknowledged on the Korean A. thaliana chloroplast genome, indicating an identical number of SSRs on the remaining 5 chloroplast genomes with a alternative of sequence variations in the direction of the SSR space. A nucleotide vary analysis revealed two extraordinarily variable areas on A. thaliana chloroplast genomes. Phylogenetic timber with three additional chloroplast genomes of East Asian pure isolates current that Korean and Chinese language language pure isolates are clustered collectively, whereas two Japanese isolates aren’t clustered, suggesting the need for additional investigations of the chloroplast genomes of East Asian isolates.

 

Loci acknowledged by a genome-wide affiliation study of carotid artery stenosis inside the eMERGE neighborhood

 

Carotid artery atherosclerotic sickness (CAAD) is a risk subject for stroke. We used a genome-wide affiliation (GWAS) technique to seek out genetic variants associated to CAAD in members inside the digital Medical Data and Genomics (eMERGE) Group. We acknowledged grownup CAAD situations with unilateral or bilateral carotid artery stenosis and controls with out proof of stenosis from digital nicely being info at eight eMERGE web sites. We carried out GWAS with a model adjusting for age, intercourse, study web site, and genetic principal components of ancestry.

 

In eMERGE we found 1793 CAAD situations and 17,958 controls. Two loci reached genome-wide significance, on chr6 in LPA (rs10455872, odds ratio [OR] (95% confidence interval [CI]) = 1.50 (1.30-1.73), p = 2.1 × 10-8 ) and on chr7, an intergenic single nucleotide variant (SNV; rs6952610, OR (95% CI) = 1.25 (1.16-1.36), p = 4.3 × 10-8 ). The chr7 affiliation remained very important inside the presence of the LPA SNV as a covariate. The LPA SNV was moreover associated to

 

coronary coronary coronary heart sickness (CHD; 4199 situations and 11,679 controls) on this study (OR (95% CI) = 1.27 (1.13-1.43), p = 5 × 10-5 ) nonetheless the chr7 SNV was not (OR (95% CI) = 1.03 (0.97-1.09), p = .37). Every variants replicated in UK Biobank. Elevated lipoprotein(a) concentrations ([Lp(a)]) and LPA variants associated to elevated [Lp(a)] have beforehand been associated to CAAD and CHD, along with rs10455872. With digital nicely being file phenotypes in eMERGE and UKB, we replicated a beforehand acknowledged affiliation and acknowledged a novel locus associated to CAAD.

Immunophenotypic Landscape and Prognosis of Diffuse Large B-Cell Lymphoma with MYC/BCL2 Double Expression: An Analysis of A Prospectively Immunoprofiled Cohort

Diffuse large B-cell lymphoma (DLBCL) patients with MYC/BCL2 double expression (DE) show poor prognosis and their clinical outcomes after R-CHOP therapy vary immensely. We investigated the prognostic value of DE in aggressive B-cell lymphoma patients (n = 461), including those with DLBCL (n = 417) and high-grade B-cell lymphoma (HGBL; n = 44), in a prospectively immunoprofiled cohort. DE was observed in 27.8% of DLBCLs and 43.2% of HGBLs (P = 0.058). DE-DLBCL patients were older (P = 0.040) and more frequently exhibited elevated serum LDH levels (P = 0.002), higher international prognostic index (IPI; P = 0.042), non-germinal-center B-cell phenotype (P < 0.001), and poor response to therapy (P = 0.042) compared to non-DE-DLBCL patients.
In R-CHOP-treated DLBCL patients, DE status predicted poor PFS and OS independently of IPI (P < 0.001 for both). Additionally, in DE-DLBCL patients, older age (>60 years; P = 0.017), involvement of ³2 extranodal sites (P = 0.021), bone marrow involvement (P = 0.001), high IPI (P = 0.017), CD10 expression (P = 0.006), poor performance status (P = 0.028), and elevated LDH levels (P < 0.001) were significantly associated with poor OS.
Notably, DE-DLBCL patients with normal LDH levels exhibited similar PFS and OS to those of patients with non-DE-DLBCL. Our findings suggest that MYC/BCL2 DE predicts poor prognosis in DLBCL. Risk stratification of DE-DLBCL patients based on LDH levels may guide clinical decision-making for DE-DLBCL patients.
hicstatistics
hicstatistics

Resveratrol relieves chlorothalonil-induced apoptosis and necroptosis through miR-15a/Bcl2-A20 axis in fish kidney cells

Chlorothalonil (CT) is a commonly used fungicide and its excessive application seriously threatens aquatic life and human health. Resveratrol (RSV) is a natural polyphenol and can be used as a therapeutic and preventive agent for the treatment of various diseases. To explore the toxic mechanism of CT exposure on fish kidney cell, as well as the alleviation effect of RSV, we established CT poisoning and/or RSV treatment fish kidney cell models. Ctenopharyngodon idellus kidney (CIK) cell line was treated with CT (5 μg/L) and/or RSV (10 μM) for 48 h.
The results showed that CT exposure activated cytochromeP450s (CYPs) including CYP1A1, CYP1B1 and CYP1C, caused malondialdehyde (MDA) accumulation, inhibited glutathione (GSH) levels and glutathione peroxidase (GPX) activities, increased the expression of miR-15a and downregulated BCL2 and TNFα-induced protein 3 (TNFAIP3, A20), triggered mitochondrial pathway mediated apoptosis and receptor interacting serine/threonine kinase (RIP)-dependent necroptosis in CIK cells.
However, cell death under CT exposure could be relieved by RSV treatment through inhibiting the expression of CYP1 family genes and restoring miR-15a/BCL2-A20 axis disorders. Overall, we conclude that RSV could relieve CT-induced apoptosis and necroptosis through miR-15a/Bcl2-A20 axis in CIK cells. These results enrich the toxicological mechanisms of the CT and confirm that RSV can be used as a potential antidote for CT poisoning.

Mouse Caspase 12 (CASP12) ELISA Kit

RD-CASP12-Mu-96Tests 96 Tests
EUR 677

Anti-Caspase-12/CASP12 Antibody

PA2103 100ug/vial
EUR 334

Caspase 12 (CASP12) Antibody

abx026563-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

abx026563-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

abx216233-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

20-abx213378
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

20-abx210324
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

20-abx100899
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase 12 (CASP12) Antibody

20-abx111421
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

20-abx129818
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase 12 (Casp12) Antibody

20-abx318989
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

20-abx324638
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody

20-abx318255
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse)

4-PAA682Mu01
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12)

Recombinant Caspase 12 (CASP12)

4-RPA682Mu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: O08736
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 79.6kDa
  • Isoelectric Point: 6.1
Description: Recombinant Mouse Caspase 12 expressed in: E.coli

Recombinant Caspase 12 (CASP12)

4-RPA682Ra01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q920D5
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 31.4kDa
  • Isoelectric Point: 5.1
Description: Recombinant Rat Caspase 12 expressed in: E.coli

Caspase 12 (Casp12) Antibody (HRP)

20-abx318990
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (Casp12) Antibody (FITC)

20-abx318991
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (Casp12) Antibody (Biotin)

20-abx318992
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody (HRP)

20-abx316303
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody (FITC)

20-abx316304
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Antibody (Biotin)

20-abx316305
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse), APC

4-PAA682Mu01-APC
  • EUR 329.00
  • EUR 3041.00
  • EUR 854.00
  • EUR 416.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with APC.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse), Biotinylated

4-PAA682Mu01-Biotin
  • EUR 299.00
  • EUR 2288.00
  • EUR 684.00
  • EUR 363.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with Biotin.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse), Cy3

4-PAA682Mu01-Cy3
  • EUR 397.00
  • EUR 4013.00
  • EUR 1097.00
  • EUR 513.00
  • EUR 241.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with Cy3.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse), FITC

4-PAA682Mu01-FITC
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with FITC.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse), HRP

4-PAA682Mu01-HRP
  • EUR 302.00
  • EUR 2652.00
  • EUR 756.00
  • EUR 377.00
  • EUR 200.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with HRP.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse), PE

4-PAA682Mu01-PE
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with PE.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat)

4-PAA682Ra01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Thr244)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Caspase 12 (CASP12)

Mouse Caspase 12 (CASP12) Protein

20-abx167225
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Rat Caspase 12 (CASP12) Protein

20-abx065753
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse), APC-Cy7

4-PAA682Mu01-APC-Cy7
  • EUR 538.00
  • EUR 5962.00
  • EUR 1588.00
  • EUR 713.00
  • EUR 304.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with APC-Cy7.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat), APC

4-PAA682Ra01-APC
  • EUR 340.00
  • EUR 3203.00
  • EUR 894.00
  • EUR 432.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Thr244)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Caspase 12 (CASP12). This antibody is labeled with APC.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat), Biotinylated

4-PAA682Ra01-Biotin
  • EUR 307.00
  • EUR 2407.00
  • EUR 714.00
  • EUR 375.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Thr244)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Caspase 12 (CASP12). This antibody is labeled with Biotin.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat), Cy3

4-PAA682Ra01-Cy3
  • EUR 411.00
  • EUR 4229.00
  • EUR 1151.00
  • EUR 535.00
  • EUR 248.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Thr244)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Caspase 12 (CASP12). This antibody is labeled with Cy3.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat), FITC

4-PAA682Ra01-FITC
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Thr244)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Caspase 12 (CASP12). This antibody is labeled with FITC.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat), HRP

4-PAA682Ra01-HRP
  • EUR 311.00
  • EUR 2792.00
  • EUR 791.00
  • EUR 391.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Thr244)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Caspase 12 (CASP12). This antibody is labeled with HRP.

Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat), PE

4-PAA682Ra01-PE