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Postharvest Treatment of Hydrogen Sulfide Delays the Softening of Chilean Strawberry Fruit by Downregulating the Expression of Key Genes Involved in Pectin Catabolism
Hydrogen sulfide (H2S) performs a number of physiological roles in crops. Regardless of the proof, the position of H2S on cell wall disassembly and its implications on fleshy fruit firmness stays unknown. On this work, the impact of H2S therapy on the shelf-life, cell wall polymers and cell wall modifying-related gene expression of Chilean strawberry (Fragaria chiloensis) fruit was examined throughout postharvest storage.
The therapy with H2S extended the shelf-life of fruit by an impact of optimum dose. Fruit handled with 0.2 mM H2S maintained considerably increased fruit firmness than non-treated fruit, lowering its decay and tripling its shelf-life. Moreover, H2S therapy delays pectin degradation all through the storage interval and considerably downregulated the expression of genes encoding for pectinases, corresponding to polygalacturonase, pectate lyase, and expansin.
This proof means that H2S as a gasotransmitter prolongs the post-harvest shelf-life of the fruit and prevents its quick softening fee by a downregulation of the expression of key pectinase genes, which results in a decreased pectin degradation.

The Lipid-Modulating Impact of Tangeretin on the Inhibition of Angiopoietin-like 3 (ANGPTL3) Gene Expression via Regulation of LXRα Activation in Hepatic Cells

The extreme accumulation of TG-rich lipoproteins (TGRLs) in plasma is related to dyslipidemia and atherosclerotic cardiovascular illnesses (ASCVDs). Tangeretin is a bioactive pentamethoxyflavone primarily present in citrus peels, and it has been reported to guard towards hyperlipidemia, diabetes, and weight problems. The intention of this examine was to research the lipid-modulating results and the underlying mechanisms of tangeretin motion in hepatic cells.
Transcriptome and bioinformatics analyses with the Gene Ontology (GO) database confirmed that tangeretin considerably regulated a set of 13 differentially expressed genes (DEGs) related to the regulation of lipoprotein lipase (LPL) exercise. Amongst these DEGs, angiopoietin-like 3 (ANGPTL3), an important inhibitor of LPL catalytic exercise that regulates TGRL metabolism in plasma, was markedly downregulated by tangeretin. We demonstrated that tangeretin considerably inhibited the mRNA expression of ANGPTL3 in HepG2 and Huh-7 cells. Tangeretin therapy of hepatic cells additionally lowered the degrees of each intracellular and secreted ANGPTL3 proteins. Furthermore, we discovered that inhibition of ANGPTL3 manufacturing by tangeretin augmented LPL exercise.
We additional demonstrated that the transcriptional exercise of the ANGPTL3 promoter was considerably attenuated by tangeretin, and we recognized a DNA aspect positioned between the -250 and -121 positions that responded to tangeretin. Moreover, we discovered that tangeretin didn’t alter the degrees of the nuclear liver X receptor α (LXRα) protein, an important transcription issue that binds to the tangeretin-responsive aspect, however it could actually counteract LXRα-mediated ANGPTL3 transcription.
On the premise of molecular docking evaluation, tangeretin was predicted to bind to the ligand-binding area of LXRα, which might lead to suppression of LXRα activation. Our findings help the speculation that tangeretin exerts a lipid-lowering impact by modulating the LXRα-ANGPTL3-LPL pathway, and thus, it may be used as a possible phytochemical for the prevention or therapy of dyslipidemia.

Factors of View on the Instruments for Genome/Gene Modifying

Theoretically, a DNA sequence-specific recognition protein that may distinguish a DNA sequence equal to or greater than 16 bp might be distinctive to mammalian genomes. Lengthy-sequence-specific nucleases, corresponding to naturally occurring Homing Endonucleases and artificially engineered ZFN, TALEN, and Cas9-sgRNA, have been developed and broadly utilized in genome enhancing. In distinction to different counterparts, which acknowledge DNA goal websites by the protein moieties themselves, Cas9 makes use of a single-guide RNA (sgRNA) as a template for DNA goal recognition.
As a result of simplicity in designing and synthesizing a sgRNA for a goal website, Cas9-sgRNA has turn into essentially the most present software for genome enhancing. Furthermore, the RNA-guided DNA recognition exercise of Cas9-sgRNA is impartial of each of the nuclease actions of it on the complementary strand by the HNH area and the non-complementary strand by the RuvC area, and HNH nuclease exercise null mutant (H840A) and RuvC nuclease exercise null mutant (D10A) had been recognized.
In accompaniment with the sgRNA, Cas9, Cas9(D10A), Cas9(H840A), and Cas9(D10A, H840A) can be utilized to attain double strand breakage, complementary strand breakage, non-complementary strand breakage, and no breakage on-target website, respectively. Based mostly on such distinctive traits, many engineered enzyme actions, corresponding to DNA methylation, histone methylation, histone acetylation, cytidine deamination, adenine deamination, and primer-directed mutation, might be launched inside or across the goal website.
In an effort to stop off-targeting by the lasting expression of Cas9 derivatives, numerous transient expression strategies, together with the direct supply of Cas9-sgRNA riboprotein, had been developed. The difficulty of biosafety is indispensable in in vivo purposes; Cas9-sgRNA packaged into virus-like particles or extracellular vesicles have been designed and a few in vivo therapeutic trials have been reported.
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De Novo Transcriptome Meeting, Practical Annotation, and Transcriptome Dynamics Analyses Reveal Stress Tolerance Genes in Mangrove Tree ( Bruguiera gymnorhiza)

Their excessive adaptability to troublesome coastal circumstances makes mangrove bushes a precious useful resource and an fascinating mannequin system for understanding the molecular mechanisms underlying stress tolerance and adaptation of crops to the annoying environmental circumstances. On this examine, we used RNA sequencing (RNA-Seq) for de novo assembling and characterizing the Bruguiera gymnorhiza (L.) Lamk leaf transcriptome. B. gymnorhiza is likely one of the most generally distributed mangrove species from the largest household of mangroves; Rhizophoraceae. The de novo meeting was adopted by useful annotations and identification of particular person transcripts and gene households which are concerned in abiotic stress response.
We then in contrast the genome-wide expression profiles between two populations of B. gymnorhiza, rising beneath totally different ranges of stress, of their pure habitats. One inhabitants residing in excessive salinity atmosphere, within the shore of the Pacific Ocean- Japan, and the opposite inhabitants residing about one kilometre farther from the ocean, and subsequent to the estuary of a river; in much less saline and extra brackish situation.
Many genes concerned in response to salt and osmotic stress, confirmed elevated expression ranges in bushes rising subsequent to the ocean in excessive salinity situation. Validation of those genes might contribute to future salt-resistance analysis in mangroves and different woody crops. Moreover, the sequences and transcriptome information offered on this examine are precious scientific assets for future comparative transcriptome analysis in crops rising beneath annoying circumstances.

 

 

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The impact of anionic polymers on gene delivery: how composition and assembly help evading the toxicity-efficiency dilemma
Cationic polymers have been broadly studied for non-viral gene supply on account of their means to bind genetic materials and to work together with mobile membranes. Nonetheless, their charged nature carries the danger of elevated cytotoxicity and interplay with serum proteins, limiting their potential in vivo utility. Due to this fact, hydrophilic or anionic shielding polymers are utilized to counteract these results. Herein, a sequence of micelle-forming and micelle-shielding polymers have been synthesized through RAFT polymerization.
The copolymer poly[(n-butyl acrylate)-b-(2-(dimethyl amino)ethyl acrylamide)] (P(nBA-b-DMAEAm)) was assembled into cationic micelles and totally different shielding polymers have been utilized, i.e., poly(acrylic acid) (PAA), poly(4-acryloyl morpholine) (PNAM) or P(NAM-b-AA) block copolymer. These techniques have been in comparison with a triblock terpolymer micelle comprising PAA as the center block. The assemblies have been investigated relating to their morphology, interplay with pDNA, cytotoxicity, transfection effectivity, polyplex uptake and endosomal escape.
The bare cationic micelle exhibited superior transfection effectivity, however elevated cytotoxicity. The addition of protecting polymers led to diminished toxicity. Particularly, the triblock terpolymer micelle satisfied with excessive cell viability and no important loss in effectivity. The very best shielding impact was achieved by layering micelles with P(NAM-b-AA) supporting the colloidal stability at impartial zeta potential and utterly restoring cell viability whereas sustaining reasonable transfection efficiencies. The excessive potential of this micelle-layer-combination for gene supply was illustrated for the primary time.

Genetic Evaluation, Inhabitants Construction, and Characterisation of Multidrug-Resistant Klebsiella pneumoniae from the Al-Hofuf Area of Saudi Arabia

Multidrug-resistant Klebsiella pneumoniae (MDR-KP) is a significant public well being drawback that’s globally related to illness outbreaks and excessive mortality charges. Because the world seeks options to such pathogens, international and regional surveillance is required. The goal of the current research was to look at the antimicrobial susceptibility sample and clonal relatedness of Klebsiella pneumoniae isolates collected for a interval of three years by way of pulse discipline gel electrophoresis (PFGE).
Isolate IDs, antimicrobial assays, ESBL-production, and minimal inhibitory concentrations (MICs) have been examined with the Vitek 2 Compact Automated System. IDs have been confirmed by 16S rRNA gene sequencing, with the ensuing sequences being deposited in NCBI databases. DNA was extracted and resistance genes have been detected by PCR amplification with applicable primers. Isolates have been intensive (31%) and multidrug-resistant (65%).
Pulsotype clusters grouped the isolates into 22 band profiles that confirmed no particular sample with phenotypes. Of the isolates, 98% have been ESBL-KP, 69% have been carbapenem-resistant Enterobacteriaceae (CRE) strains, and 72.5% comprised the carriage of two MBLs (SIM and IMP). Integrons (ISAba1, ISAba2, and IS18) have been detected in 69% of the MDR-KP. Moreover, OXA-23 was detected in 67% of the isolates. This research subsequently demonstrates clonal range amongst scientific Ok. pneumoniae, confirming that this bacterium has entry to an infinite pool of genes that confer excessive resistance-developing potential.

Full Genome Sequencing of Leptospira interrogans Isolates from Malaysia Reveals Large Genome Rearrangement however Excessive Conservation of Virulence-Related Genes

The power of Leptospirae to persist in environments and animal hosts however to trigger clinically extremely variable illness in people has made leptospirosis the most typical zoonotic illness. Contemplating the paucity of knowledge on variation in full genomes of human pathogenic Leptospirae, we’ve used a mix of Single Molecule Actual-Time (SMRT) and Illumina sequencing to acquire full genome sequences of six human scientific L. interrogans isolates from Malaysia.
  • All six contained the bigger (4.28-4.56 Mb) and smaller (0.34-0.395 Mb) chromosome typical of human pathogenic Leptospirae and 0-7 plasmids. Solely 24% of the plasmid sequences could possibly be matched to databases. We recognized a chromosomal core genome of 3318 coding sequences and strain-specific accent genomes of 49-179 coding sequences.
  • These sequences enabled detailed genomic pressure typing (Genome BLAST Distance Phylogeny, DNA-DNA hybridization, and multi locus sequence typing) and phylogenetic classification (whole-genome SNP genotyping). Regardless that there was some shared synteny and collinearity throughout the six genomes, there was proof of main genome rearrangement, doubtless pushed by horizontal gene switch and homologous recombination.
  • Cellular genetic parts have been recognized in all strains in extremely various numbers, together with within the rfb locus, which defines serogroups and contributes to immune escape and pathogenesis. Then again, there was excessive conservation of virulence-associated genes together with these referring to sialic acid, alginate, and lipid A biosynthesis.
  • These findings counsel (i) that the antigenic variation, adaption to numerous host environments, and broad spectrum of virulence of L. interrogans are partially on account of a excessive diploma of genomic plasticity and (ii) that human pathogenic strains keep a core set of genes required for virulence.
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Genomic Analyses of Penicillium Species Have Revealed Patulin and Citrinin Gene Clusters and Novel Loci Concerned in Oxylipin Manufacturing

Blue mildew of apple is attributable to a number of totally different Penicillium species, amongst which P. expansum and P. solitum are essentially the most ceaselessly remoted. P. expansum is essentially the most aggressive species, and P. solitum could be very weak when infecting apple fruit throughout storage. On this research, we report full genomic analyses of three totally different Penicillium species: P. expansum R21 and P. crustosum NJ1, remoted from saved apple fruit; and Pmaximae 113, remoted in 2013 from a flooded house in New Jersey, USA, within the aftermath of Hurricane Sandy. Patulin and citrinin gene cluster analyses defined the shortage of patulin manufacturing in NJ1 in comparison with R21 and lack of citrinin manufacturing in all three strains.
Drosophila bioassay demonstrated that volatiles emitted by Psolitum SA and Ppolonicum RS1 have been extra poisonous than these from Pexpansum and P. crustosum strains (R27, R11, R21, G10, and R19). The toxicity was hypothesized to be associated to manufacturing of eight-carbon oxylipins. Putative lipoxygenase genes have been recognized in Pexpansum and Pmaximae strains, however not in Pcrustosum. Our information will present a greater understanding of Penicillium spp. complicated secondary metabolic capabilities, particularly regarding the genetic bases of mycotoxins and poisonous VOCs.
Pig-to-human xenotransplantation appears to be the response to the up to date scarcity of tissue/organ donors. Sadly, the phylogenetic distance between pig and human implies hyperacute xenograft rejection. On this research, we examined the speculation that combining expression of human α1,2-fucosyltransferase (hFUT2) and α-galactosidase A (hGLA) genes would enable for removing of this impediment in porcine transgenic epidermal keratinocytes (PEKs). We sought to find out not solely the expression profiles of recombinant human α1,2-fucosyltransferase (rhα1,2-FT) and α-galactosidase A (rhα-Gal A) proteins, but in addition the relative abundance (RA) of Galα1→3Gal epitopes within the PEKs stemming from not solely hFUT2 or hGLA single-transgenic and hFUT2×hGLA double-transgenic pigs. Our confocal microscopy and Western blotting analyses revealed that each rhα1,2-FT and rhα-Gal A enzymes have been overabundantly expressed in respective transgenic PEK traces.
Furthermore, the semiquantitative ranges of Galα1→3Gal epitope that have been assessed by lectin fluorescence and lectin blotting have been discovered to be considerably diminished in every variant of genetically modified PEK line as in comparison with these noticed within the management nontransgenic PEKs. Notably, the bi-transgenic PEKs have been characterised by considerably lessened (however nonetheless detectable) RAs of Galα1→3Gal epitopes as in comparison with these recognized for each varieties of mono-transgenic PEK traces. Moreover, our present investigation confirmed that the coexpression of two protecting transgenes gave rise to enhanced abrogation of Galα→3Gal epitopes in hFUT2×hGLA double-transgenic PEKs.
To summarize, detailed estimation of semiquantitative profiles for human α-1,2-FT and α-Gal A proteins adopted by identification of the extent of abrogating the abundance of Galα1→3Gal epitopes within the ex vivo expanded PEKs stemming from mono- and bi-transgenic pigs have been discovered to be a sine qua non situation for effectively ex situ defending steady traces of skin-derived somatic cells inevitable in additional research.
The latter is because of be targeted on figuring out epigenomic reprogrammability of single- or double-transgenic cell nuclei inherited from grownup cutaneous keratinocytes in porcine nuclear-transferred oocytes and corresponding cloned embryos. To our data, this idea was proven to signify a very new strategy designed to generate and multiply genetically reworked pigs by somatic cell cloning for the wants of reconstructive drugs and dermoplasty-mediated tissue engineering of human integumentary system.
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Epigenetic and Genetic Integrity, Metabolic Stability, and Field Performance of Cryopreserved Plants
Cryopreservation is taken into account an excellent technique for the long-term preservation of plant genetic assets. Important progress was achieved over the previous a number of many years, ensuing within the profitable cryopreservation of the genetic assets of various plant species. Cryopreservation procedures typically make use of in vitro tradition methods and require the exact management of a number of steps, such because the excision of explants, preculture, osmo- and cryoprotection, dehydration, freeze-thaw cycle, unloading, and post-culture for the restoration of vegetation.
These processes create a worrying surroundings and trigger reactive oxygen species (ROS)-induced oxidative stress, which is detrimental to the expansion and regeneration of tissues and vegetation from cryopreserved tissues. ROS-induced oxidative stresses had been documented to induce (epi)genetic and somatic variations.
Subsequently, the event of true-to-type regenerants of the supply germplasm is of major concern within the utility of plant cryopreservation know-how. The current article supplies a complete evaluation of epigenetic and genetic integrity, metabolic stability, and discipline efficiency of cryopreserved vegetation developed prior to now decade. Potential areas and the instructions of future analysis in plant cryopreservation are additionally proposed.

Dosage-Dependent Gynoecium Improvement and Gene Expression in Brassica napus-Orychophragmus violaceus Addition Traces

Distant hybridization often results in feminine sterility of the hybrid however the mechanism behind that is poorly understood. Full pistil abortion however regular male fertility was proven by one Brassica napus-Orychophragmus violaceus monosomic alien addition line (MA, AACC + 1 IO, 2n = 39) produced beforehand. To review the impact of a single O. violaceus chromosome addition on pistil improvement in numerous genetic backgrounds, hybrids between the MA and B. carinata (BBCC), B. juncea (AABB), and two artificial hexaploids (AABBCC) had been firstly produced on this research which present full feminine sterility.
A microspore tradition was additional carried out to provide the haploid monosomic alien addition line (HMA, AC + 1 IO, 2n = 20) and disomic addition line (DA, AACC + 2 IO, 2n = 40) along with haploid (H, AC, 2n = 19) and double haploid (DH, AACC, 2n = 38) vegetation of B. napus from MA to analyze the dosage impact of the alien O. violaceus chromosome on pistil improvement and gene expression. In comparison with MA, the event of the pistils of DA and HMA was fully or partially recovered, wherein the pistils might swell and elongate to a traditional form after open pollination, though no seeds had been produced.
Comparative RNA-seq analyses revealed that the numbers of the differentially expressed genes (DEGs) had been considerably totally different, dosage-dependent, and in step with the phenotypic distinction in pairwise comparisons of HMA vs. H, DA vs. DH, MA vs. DH, MA vs. DA, and MA vs. HMA. The gene ontology (GO) enrichment evaluation of DEGs confirmed that a lot of genes concerned within the improvement of the gynoecium, embryo sac, ovule, and integuments. Significantly, a number of frequent DEGs for pistil improvement shared in HMA vs. H and DA vs. DH confirmed capabilities in genotoxic stress response, auxin transport, and signaling and adaxial/abaxial axis specification. The outcomes supplied up to date data for the molecular mechanisms behind the gynoecium improvement of B. napus responding to the dosage of alien O. violaceus chromosomes.

Courting the Frequent Ancestor from an NCBI Tree of 83688 Excessive-High quality and Full-Size SARS-CoV-2 Genomes

All relationship research involving SARS-CoV-2 are problematic. Earlier research have dated the latest frequent ancestor (MRCA) between SARS-CoV-2 and its shut kin from bats and pangolins. Nevertheless, the evolutionary price thus derived is predicted to vary from the speed estimated from sequence divergence of SARS-CoV-2 lineages. Right here, I current relationship outcomes for the primary time from a big phylogenetic tree with 86,582 high-quality full-length SARS-CoV-2 genomes.
  • The tree accommodates 83,688 genomes with full specification of assortment time. Such a big tree spanning a interval of about 1.5 years gives a superb alternative for relationship the MRCA of the sampled SARS-CoV-2 genomes. The MRCA is dated 16 August 2019, with the evolutionary price estimated to be 0.05526 mutations/genome/day.
  • The Pearson correlation coefficient (r) between the root-to-tip distance (D) and the gathering time (T) is 0.86295. The NCBI tree additionally consists of 10 SARS-CoV-2 genomes remoted from cats, collected over roughly the identical time span as human COVID-19 an infection.
  • The MRCA from these cat-derived SARS-CoV-2 is dated 30 July 2019, with r = 0.98464. Whereas the relationship technique is well-known, I’ve included detailed illustrations in order that anybody can repeat the evaluation and acquire the identical relationship outcomes.
  • With 16 August 2019 because the date of the MRCA of sampled SARS-CoV-2 genomes, archived samples from respiratory or digestive tracts collected round or earlier than 16 August 2019, or these that aren’t descendants of the prevailing SARS-CoV-2 lineages, must be significantly invaluable for tracing the origin of SARS-CoV-2.
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Genome-Broad Identification of the HMA Gene Household and Expression Evaluation underneath Cd Stress in Barley

Lately, cadmium (Cd) air pollution in soil has elevated with growing industrial actions, which has restricted crop progress and agricultural improvement. The heavy metallic ATPase (HMA) gene household contributes to heavy metallic stress resistance in vegetation. On this research, 21 HMA genes (HvHMAs) had been recognized in barley (Hordeumvulgare L., Hv) utilizing bioinformatics strategies. Primarily based on phylogenetic evaluation and area distribution, barley HMA genes had been divided into 5 teams (A-E), and full analyses had been carried out by way of physicochemical properties, structural traits, conserved domains, and chromosome localization.
The expression sample evaluation confirmed that almost all HvHMA genes had been expressed in barley and exhibited tissue specificity. In response to the fragments per kilobase of exon per million fragments values in shoots from seedlings on the 10 cm shoot stage (LEA) and phylogenetic evaluation, 5 HvHMA genes had been chosen for expression evaluation underneath Cd stress. Among the many 5 HvHMA genes, three (HvHMA1HvHMA3, and HvHMA4) had been upregulated and two (HvHMA2 and HvHMA6) had been downregulated following Cd remedies. This research serves as a basis for clarifying the capabilities of HvHMA proteins within the heavy metallic stress resistance of barley.

Carbon Dioxide-Derived Biodegradable and Cationic Polycarbonates as a New siRNA Service for Gene Remedy in Pancreatic Most cancers

Pancreatic most cancers is an aggressive malignancy related to poor prognosis and a excessive tendency in growing infiltration and metastasis. Okay-ras mutation is a significant genetic dysfunction in pancreatic most cancers affected person. RNAi-based therapies may be employed for combating pancreatic most cancers by silencing Okay-ras gene expression. Nevertheless, the medical utility of RNAi know-how is appreciably restricted by the dearth of a correct siRNA supply system.
To deal with this hurdle, cationic poly (cyclohexene carbonate) s (CPCHCs) utilizing broadly sourced CO2 because the monomer are subtly synthesized through ring-opening copolymerization (ROCOP) and thiol-ene functionalization. The developed CPCHCs might successfully encapsulate therapeutic siRNA to kind CPCHC/siRNA nanoplexes (NPs). Serving as a siRNA service, CPCHC possesses biodegradability, negligible cytotoxicity, and excessive transfection effectivity. In vitro research exhibits that CPCHCs are able to successfully defending siRNA from being degraded by RNase and selling a sustained endosomal escape of siRNA.
After therapy with CPCHC/siRNA NPs, the Okay-ras gene expression in each pancreatic most cancers cell line (PANC-1 and MiaPaCa-2) are considerably down-regulated. Subsequently, the cell progress and migration are significantly inhibited, and the handled cells are induced into cell apoptotic program. These outcomes exhibit the promising potential of CPCHC-mediated siRNA therapies in pancreatic most cancers therapy.

 

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A Gene-Expression Predictor for Efficacy of Induction Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma

Background: Induction chemotherapy (IC) adopted by concurrent chemoradiotherapy is the mainstay therapy for sufferers with locoregionally superior nasopharyngeal carcinoma. Nonetheless, some sufferers acquire little profit and expertise pointless poisonousities from IC. We supposed to develop a gene-expression signature that may establish beneficiaries of IC.

 

Strategies: We screened chemosensitivity-related genes by evaluating gene-expression profiles of sufferers with short-term tumor response or nonresponse to IC (n = 95) utilizing microarray evaluation. Chemosensitivity-related genes had been quantified by digital expression profiling in a coaching cohort (n = 342) to acquire a gene signature. We then validated this gene signature within the scientific trial cohort (n = 187) and an exterior impartial cohort (n = 240). Assessments of statistical significance are 2-sided.

 

Outcomes: We recognized 43 chemosensitivity-related genes related to the short-term tumor response to IC. Within the coaching cohort, a 6-gene signature was developed that was extremely correct at predicting the short-term tumor response to IC (space below the curve [AUC] = 0.87, sensitivity = 87.5%, specificity = 75.6%).

We additional discovered that IC conferred failure-free survival advantages solely in sufferers within the profit group (hazard ratio [HR] = 0.54, 95% confidence interval [CI] = 0.34 to 0.87; P = .01) and never on these within the no-benefit group (HR = 1.25, 95% CI = 0.62 to 2.51; P = .53). Within the scientific trial cohort, the 6-gene signature was additionally extremely correct at predicting the tumor response (AUC = 0.82, sensitivity = 87.5%, specificity = 71.8%) and indicated failure-free survival advantages. Within the exterior impartial cohort, comparable outcomes had been noticed.

 

Conclusions: The 6-gene signature will help choose beneficiaries of IC and lay a basis for a extra individualized therapeutic technique for locoregionally superior nasopharyngeal carcinoma sufferers.

 

Genetic Occasions and Signaling Mechanisms Underlying Schwann Cell Destiny in Improvement and Most cancers

 

On this assessment, we describe Schwann cell improvement from embryonic neural crest cells to terminally differentiated myelinated and nonmyelinated mature Schwann cells. We deal with the genetic drivers and signaling mechanisms mediating choices to proliferate versus differentiate throughout Schwann cell improvement, highlighting pathways that overlap with Schwann cell improvement and are dysregulated in tumorigenesis.

We conclude by contemplating how our data of the occasions underlying Schwann cell improvement and mouse fashions of schwannoma, neurofibroma, and malignant peripheral nerve sheath tumor can inform novel therapeutic methods for sufferers with cancers derived from Schwann cell lineages.

The event and controversy of aggressive endogenous RNA speculation in non-coding genes

As a momentous post-transcriptional regulator, microRNAs (miRNAs) are attracting increasingly more consideration. The classical miRNAs regulated mechanism exhibits it binds to the targets’ 3’UTR thus play the function in post-transcription.

In the meantime, single miRNA can goal a number of genes, so these ought to compete to bind that miRNA. Vice versa, single gene can sponge mass of miRNAs as nicely. Thus the aggressive endogenous RNAs (ceRNAs) speculation was put ahead in 2011.

The ceRNA speculation has made big achievements, particularly in non-coding genes, which together with lengthy non-coding RNAs (lncRNAs), circle RNAs (circRNAs) and pseudogenes, even viral transcripts. It additionally contributed enormously to epigenetics improvement.

Nonetheless, an growing variety of controversies have occurred with applause. Primarily based on this example, this assessment introduces one thing in element in regards to the ceRNAs speculation achieved in lncRNAs,circRNAs, pseudogenes and viral transcripts, respectively. In the meantime, it additionally covers controversy of the ceRNAs speculation

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Conserved Patterns in Developmental Processes and Phases, Somewhat than Genes, Unite the Extremely Divergent Bilateria 

  • Bilateria are the predominant clade of animals on Earth. Regardless of having developed all kinds of physique plans and developmental modes, they’re characterised by frequent morphological traits. By default, researchers have tried to hyperlink clade-particular genes to those traits, thus distinguishing bilaterians from non-bilaterians, by their gene content material.
  • Right here we argue that it’s relatively organic processes that unite Bilateria and set them aside from their non-bilaterian sisters, with a much less advanced physique morphology. To check this speculation, we in contrast proteomes of bilaterian and non-bilaterian species in an elaborate computational pipeline, aiming to seek for a set of bilaterian-specific genes. Regardless of the restricted confidence of their bilaterian specificity, we however detected Bilateria-specific practical and developmental patterns within the sub-set of genes conserved in distantly associated Bilateria.

 

  • Utilizing a novel multi-species GO-enrichment technique, we decided the practical repertoire of genes which might be extensively conserved amongst Bilateria. Analyzing expression profiles in three very distantly associated mannequin species- melanogasterD. rerioand C. elegans-we discover attribute peaks at comparable phases of improvement and a delayed onset of expression in embryos. Particularly, the expression of the conserved genes seems to peak on the phylotypic stage of various bilaterian phyla.

 

  • In abstract, our examine illustrate how improvement connects distantly associated Bilateria after thousands and thousands of years of divergence, pointing to processes doubtlessly separating them from non-bilaterians. We argue that evolutionary biologists ought to return from a purely gene-centric view of evolution and place extra deal with analyzing and defining conserved developmental processes and durations.

The efficacy of chemotherapeutic drug mixtures could also be predicted by concordance of gene response to the one brokers

Figuring out the expression of genes in response to completely different courses of chemotherapeutic medicine could permit for a greater understanding as to which can be used successfully together. Within the current examine, the human colorectal most cancers cell line HCT116 was cultured with equi-active concentrations of a sequence of anti-cancer brokers.

Gene expression profiles had been then measured by whole-genome microarray. Though every drug induced a singular signature of gene expression in tumour cells, there have been marked similarities between sure medicine, even in these from completely different courses. For instance, the antimalarial agent artesunate and the platinum-containing alkylating agent, oxaliplatin, produced a really comparable mRNA expression sample in HCT116 cells with ~14,000 genes being affected by the 2 medicine in the identical method.

Moreover, the general correlation of gene responses between two brokers may predict whether or not their use together would result in a higher or lesser impact on cell quantity, decided experimentally, than predicted by single agent experiments. The outcomes indicated that even when working by means of completely different mechanisms, combining medicine that provoke an identical transcriptional response could represent the most suitable choice for figuring out drug-combination methods for the therapy of most cancers.

 

Human Pim-3 Oncogene (PIM3) ELISA Kit

DLR-PIM3-Hu-96T 96T
EUR 725
  • Should the Human Pim-3 Oncogene (PIM3) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Pim-3 Oncogene (PIM3) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Pim-3 Oncogene (PIM3) ELISA Kit

RDR-PIM3-Hu-48Tests 48 Tests
EUR 589

Human Pim-3 Oncogene (PIM3) ELISA Kit

RDR-PIM3-Hu-96Tests 96 Tests
EUR 820

Human Pim-3 Oncogene (PIM3) ELISA Kit

RD-PIM3-Hu-48Tests 48 Tests
EUR 563

Human Pim-3 Oncogene (PIM3) ELISA Kit

RD-PIM3-Hu-96Tests 96 Tests
EUR 783

Pim-3 Oncogene (PIM3) Antibody

20-abx131576
  • EUR 453.00
  • EUR 133.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Pim-3 Oncogene (PIM3) Antibody

20-abx174068
  • EUR 926.00
  • EUR 467.00
  • 1 mg
  • 200 ug
  • Please enquire.

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human)

4-PAN637Hu01
  • EUR 262.00
  • EUR 2747.00
  • EUR 679.00
  • EUR 331.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3)

Recombinant Pim-3 Oncogene (PIM3)

4-RPN637Hu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q86V86
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 39.6kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Pim-3 Oncogene expressed in: E.coli

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human), APC

4-PAN637Hu01-APC
  • EUR 368.00
  • EUR 3599.00
  • EUR 993.00
  • EUR 472.00
  • EUR 229.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3). This antibody is labeled with APC.

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human), Biotinylated

4-PAN637Hu01-Biotin
  • EUR 328.00
  • EUR 2697.00
  • EUR 786.00
  • EUR 404.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3). This antibody is labeled with Biotin.

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human), Cy3

4-PAN637Hu01-Cy3
  • EUR 449.00
  • EUR 4757.00
  • EUR 1283.00
  • EUR 588.00
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3). This antibody is labeled with Cy3.

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human), FITC

4-PAN637Hu01-FITC
  • EUR 314.00
  • EUR 2899.00
  • EUR 814.00
  • EUR 397.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3). This antibody is labeled with FITC.

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human), HRP

4-PAN637Hu01-HRP
  • EUR 335.00
  • EUR 3135.00
  • EUR 877.00
  • EUR 426.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3). This antibody is labeled with HRP.

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human), PE

4-PAN637Hu01-PE
  • EUR 314.00
  • EUR 2899.00
  • EUR 814.00
  • EUR 397.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3). This antibody is labeled with PE.

Human Pim-3 Oncogene (PIM3) Protein

20-abx650812
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human), APC-Cy7

4-PAN637Hu01-APC-Cy7
  • EUR 616.00
  • EUR 7078.00
  • EUR 1867.00
  • EUR 824.00
  • EUR 338.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3). This antibody is labeled with APC-Cy7.

Human Pim-3 Oncogene (PIM3)ELISA Kit

201-12-2347 96 tests
EUR 440
  • This Pim-3 Oncogene ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Pim-3 Oncogene (PIM3) CLIA Kit

20-abx190020
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Pim-3 Oncogene (PIM3) ELISA Kit

20-abx152746
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Pim-3 Oncogene(PIM3)ELISA Kit

QY-E04696 96T
EUR 361

Rat Pim-3 Oncogene(PIM3)ELISA Kit

QY-E10537 96T
EUR 400

Human Pim-3 Oncogene (PIM3)CLIA Kit

SCN637Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-3 Oncogene (PIM3) in tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3)CLIA Kit

SCN637Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-3 Oncogene (PIM3) in tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3)CLIA Kit

SCN637Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-3 Oncogene (PIM3) in tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3)CLIA Kit

SCN637Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-3 Oncogene (PIM3) in tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3) CLIA Kit

4-SCN637Hu
  • EUR 5698.00
  • EUR 3061.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Pim-3 Oncogene Clia kit. Alternative names of the recognized antigen: Serine/threonine-protein kinase pim-3
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Pim-3 Oncogene (PIM3)tissue homogenates and other biological fluids

Mouse Pim-3 Oncogene(PIM3)ELISA Kit

QY-E21186 96T
EUR 361

Human Pim-3 Oncogene (PIM3) ELISA Kit

SEN637Hu-10x96wellstestplate 10x96-wells test plate
EUR 5189.65
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-3 Oncogene (PIM3) in serum, plasma, tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3) ELISA Kit

SEN637Hu-1x48wellstestplate 1x48-wells test plate
EUR 515.03
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-3 Oncogene (PIM3) in serum, plasma, tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3) ELISA Kit

SEN637Hu-1x96wellstestplate 1x96-wells test plate
EUR 692.9
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-3 Oncogene (PIM3) in serum, plasma, tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3) ELISA Kit

SEN637Hu-5x96wellstestplate 5x96-wells test plate
EUR 2818.05
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-3 Oncogene (PIM3) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-3 Oncogene (PIM3) in serum, plasma, tissue homogenates and other biological fluids.

Human Pim-3 Oncogene (PIM3) ELISA Kit

4-SEN637Hu
  • EUR 5240.00
  • EUR 2769.00
  • EUR 693.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Pim-3 Oncogene elisa. Alternative names of the recognized antigen: Serine/threonine-protein kinase pim-3
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Pim-3 Oncogene (PIM3) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human PIM3 (Pim-3 Oncogene)

ELK6491 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pim-3 Oncogene (PIM3). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Pim-3 Oncoge
  • Show more
Description: A sandwich ELISA kit for detection of Pim-3 Oncogene from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Serine/Threonine-Protein Kinase Pim-3 (PIM3) Antibody

20-abx214125
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Serine/Threonine-Protein Kinase Pim-3 (PIM3) Antibody

20-abx241699
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Serine/threonine-Protein Kinase Pim-3 (PIM3) Antibody

20-abx318212
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Rabbit Pim 1 Oncogene ELISA kit

E04P0753-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Pim 1 Oncogene ELISA kit

E04P0753-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Pim 1 Oncogene ELISA kit

E04P0753-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Serine/threonine-Protein Kinase Pim-3 (PIM3) Antibody (HRP)

20-abx315070
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Serine/threonine-Protein Kinase Pim-3 (PIM3) Antibody (FITC)

20-abx315071
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Serine/threonine-Protein Kinase Pim-3 (PIM3) Antibody (Biotin)

20-abx315072
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse)

4-PAC578Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1)

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat)

4-PAC578Ra01
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1)

Pim-2 Oncogene (PIM2) Polyclonal Antibody (Human)

4-PAP797Hu01
  • EUR 262.00
  • EUR 2747.00
  • EUR 679.00
  • EUR 331.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Leu82~Glu291)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-2 Oncogene (PIM2)

Pim-2 Oncogene (PIM2) Polyclonal Antibody (Mouse)

4-PAP797Mu01
  • EUR 266.00
  • EUR 2813.00
  • EUR 694.00
  • EUR 337.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Gly98~Cys319)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-2 Oncogene (PIM2)

Pim-2 Oncogene (PIM2) Polyclonal Antibody (Rat)

4-PAP797Ra01
  • EUR 275.00
  • EUR 2958.00
  • EUR 727.00
  • EUR 350.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Leu34~Glu292)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-2 Oncogene (PIM2)

Pim-1 Oncogene (PIM1) Antibody

20-abx101233
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Pim-1 Oncogene (PIM1) Antibody

20-abx101234
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Pim-1 Oncogene (PIM1) Antibody

20-abx101235
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Pim-2 Oncogene (PIM2) Antibody

20-abx101236
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Pim-2 Oncogene (PIM2) Antibody

20-abx101237
  • EUR 481.00
  • EUR 133.00
  • EUR 1414.00
  • EUR 662.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Pim-2 Oncogene (PIM2) Antibody

20-abx129066
  • EUR 453.00
  • EUR 133.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Pim-1 Oncogene (PIM1) Antibody

abx146417-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Pim-1 Oncogene (PIM1) Antibody

20-abx174066
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Pim-2 Oncogene (PIM2) Antibody

20-abx174067
  • EUR 926.00
  • EUR 467.00
  • 1 mg
  • 200 ug
  • Please enquire.

Pim-2 Oncogene (PIM2) Antibody

abx236456-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Pim-2 Oncogene (PIM2) Antibody

abx431508-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Pim-2 Oncogene (PIM2) Antibody

abx433133-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Pim-2 Oncogene (PIM2) Antibody

abx433134-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Anti-PIM3 antibody

STJ119424 100 µl
EUR 277
Description: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), APC

4-PAC578Mu01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with APC.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Biotinylated

4-PAC578Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Cy3

4-PAC578Mu01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), FITC

4-PAC578Mu01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), HRP

4-PAC578Mu01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), PE

4-PAC578Mu01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with PE.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), APC

4-PAC578Ra01-APC
  • EUR 364.00
  • EUR 3545.00
  • EUR 980.00
  • EUR 467.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Biotinylated

4-PAC578Ra01-Biotin
  • EUR 325.00
  • EUR 2658.00
  • EUR 777.00
  • EUR 400.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Cy3

4-PAC578Ra01-Cy3
  • EUR 444.00
  • EUR 4685.00
  • EUR 1265.00
  • EUR 581.00
  • EUR 261.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), FITC

4-PAC578Ra01-FITC
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.

Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), HRP

4-PAC578Ra01-HRP
  • EUR 332.00
  • EUR 3089.00
  • EUR 866.00
  • EUR 421.00
  • EUR 213.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
hicstatistics
Melting dsDNA Donor Molecules Vastly Improves Precision Genome Enhancing in Caenorhabditiselegans

CRISPR genome modifying has revolutionized genetics in quite a few organisms. Contained in the nematode Caenorhabditiselegans one injection into every of the 2 gonad arms of an grownup hermaphrodite exposes tons of of meiotic germ cells to modifying mixtures, allowing the restoration of a variety of indels or small precision edits from every successfully injected animal. Sadly, significantly for extended insertions, modifying efficiencies can differ broadly, necessitating a variety of injections, and customarily requiring co-selection methods.

 

Correct proper right here we present that melting double stranded DNA (dsDNA) donor molecules earlier to injection will enhance the frequency of tangible homology-directed restore (HDR) by a variety of fold for longer edits. We describe troubleshooting methods that let persistently excessive modifying efficiencies ensuing, as an illustration, in as rather a lot as 100 unbiased GFP knock-ins from a single injected animal. These efficiencies make C. elegans by far the perfect metazoan to genome edit, eradicating limitations to the use and adoption of this facile system as a mannequin for understanding animal biology.

 

Water-Pipe Smoking Publicity Deregulates a Set of Genes Related to Human Head and Neck Most cancers Improvement and Prognosis

  • Water-pipe smoking (WPS) is popping into in all probability probably the most well-liked kind of tobacco use among the many many many youth, notably contained in the Coronary heart East, altering cigarettes quickly and turning into a crucial danger of tobacco dependancy worldwide. Smoke from WPS accommodates comparable toxins as these current in cigarette smoke and is linked instantly with plenty of sorts of cancers together with lung and head and neck (HN) carcinomas.

 

  • Nonetheless, the underlying molecular pathways and/or goal genes accountable for the carcinogenic course of are nonetheless unknown. On this research, human widespread oral epithelial (HNOE) cells, NanoStringPanCancer Pathways panel of 770 gene transcripts and quantitative real-time polymerase chain response (qRT-PCR) evaluation had been utilized to hunt out differentially expressed genes (DEG) modulated by WPS. In silico evaluation was carried out to analysis the have an effect on of those genes in HN most cancers affected specific particular person’s biology and consequence. We discovered that WPS can induce the epithelial-mesenchymal transition (EMT: hallmark of most cancers development) of HNOE cells.

 

  • Additional considerably, our evaluation of NanoString revealed 23 genes deregulated beneath the have an effect on of WPS, accountable for the modulation of cell cycle, proliferation, migration/invasion, apoptosis, sign transduction, and inflammatory response. Further evaluation was carried out utilizing qRT-PCR of HNOE WPS-exposed and unexposed cells supported the reliability of our NanoString data.

 

  • Furthermore, we exhibit these DEG to be upregulated in most cancers in distinction with widespread tissue. Utilizing the Kaplan-Meier evaluation, we seen a major affiliation between WPS-deregulated genes and relapse-free survival/full survival in HN most cancers victims. Our findings level out that WPS can modulate EMT together with a set of genes which may very well be instantly concerned in human HN carcinogenesis, thereby affecting HN most cancers victims’ survival.
hicstatistics
hicstatistics

A pilot research on the genetic differ of Mycobacterium tuberculosis troublesome strains from tuberculosis victims contained in the Littoral area of Cameroon

Background: The re-emergence of tuberculosis (TB) worldwide, compounded by multi-drug resistance (MDR) of the causative brokers constitutes a major concern to the administration of the illness. Speedy analysis and correct stress identification are pivotal to the administration of the illness. This pilot research investigated the genetic differ of Mycobacterium tuberculosis troublesome (MTBC) strains from TB victims contained in the Littoral area of Cameroon together with their resistance to rifampicin (RIF).

 

Victims and strategies: This was a cross sectional hospital-based research carried out between January and December 2017 and together with 158 isolates from sputum smear constructive people [105 (66.5%) males and 53 (33.5%) females]. Sputum samples had been examined utilizing Xpert MTB/RIF, adopted by customized on Lowenstein-Jensen medium. Isolates had been additional subjected to molecular characterization utilizing IS6110 typing, deletion evaluation and spoligotyping.

 

Outcomes: 13 (8.8%) of the 147 isolates with susceptibility outcomes accessible had been proof in direction of RIF. Drug resistance occurred in 5/50 (10%) feminine in contrast with 8/97 (8.2%) male (OR, 0.81; 0.25-2.62; p = 0.764), and there was no essential distinction all by means of the age ranges (p = 0.448). Nonetheless, RIF resistance was related (OR, 0.18, 95%CI, 0.05-0.69; p = 0.023) with beforehand handled victims [(4/14 (28.6%)] in contrast with new ones [9/133 (6.8%)].

The 150 acknowledged lineages included amongst others 54 (36%) Cameroon, 18 (12%) UgandaI, 32 (21.3%) Haarlem, 17 (11.3%) Ghana, 9(6%) West African 1, 7(4.7%) Delhi/CAS, 4 (2.7%) LAM and three (2%) UgandaII. Of the 150 isolates, a really highly effective cluster was the Cameroon SIT 61, with 43(28.7%) isolates. Six (35.3%) of the 17 UgandaI sub-lineage had been RIF resistant (OR, 9.58; 95%CI, 2.74-33.55, p = 0.001).

 

Conclusion: The cosmopolitan Littoral area presents with a giant Mycobacterium tuberculosis (MTB) strains differ and the UgandaI sub-lineage attainable related to RIF resistance. Understanding the unfold of this clade by the use of surveillance will improve TB administration contained in the area.

 

Human Pim-1 Oncogene (PIM1) ELISA Kit
DLR-PIM1-Hu-96T 96T
EUR 673
  • Should the Human Pim-1 Oncogene (PIM1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Pim-1 Oncogene (PIM1) ELISA Kit
DLR-PIM1-Ra-48T 48T
EUR 549
  • Should the Rat Pim-1 Oncogene (PIM1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Pim-1 Oncogene (PIM1) ELISA Kit
DLR-PIM1-Ra-96T 96T
EUR 718
  • Should the Rat Pim-1 Oncogene (PIM1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Hu-48Tests 48 Tests
EUR 544
Human Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Hu-96Tests 96 Tests
EUR 756
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Ra-48Tests 48 Tests
EUR 583
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RDR-PIM1-Ra-96Tests 96 Tests
EUR 811
Human Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Hu-48Tests 48 Tests
EUR 521
Human Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Hu-96Tests 96 Tests
EUR 723
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Ra-48Tests 48 Tests
EUR 557
Rat Pim-1 Oncogene (PIM1) ELISA Kit
RD-PIM1-Ra-96Tests 96 Tests
EUR 775
Pim-1 Oncogene (PIM1) Antibody
20-abx101233
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Pim-1 Oncogene (PIM1) Antibody
20-abx101234
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Pim-1 Oncogene (PIM1) Antibody
20-abx101235
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Pim-1 Oncogene (PIM1) Antibody
abx146417-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.
Pim-1 Oncogene (PIM1) Antibody
20-abx174066
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse)
4-PAC578Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1)
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat)
4-PAC578Ra01
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1)
Recombinant Pim-1 Oncogene (PIM1)
4-RPC578Hu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P11309
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 47.8kDa
  • Isoelectric Point: 5.8
Description: Recombinant Human Pim-1 Oncogene expressed in: E.coli
Recombinant Pim-1 Oncogene (PIM1)
4-RPC578Mu01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P06803
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 17.1kDa
  • Isoelectric Point: 5.6
Description: Recombinant Mouse Pim-1 Oncogene expressed in: E.coli
Recombinant Pim-1 Oncogene (PIM1)
4-RPC578Ra01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P26794
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 17.4kDa
  • Isoelectric Point: Inquire
Description: Recombinant Rat Pim-1 Oncogene expressed in: E.coli
Pim-1 Oncogene (PIM1) Antibody (Biotin)
20-abx271779
  • EUR 453.00
  • EUR 244.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Pim-1 Oncogene (PIM1) Antibody (Biotin)
20-abx272590
  • EUR 467.00
  • EUR 244.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Pim-1 Oncogene (PIM1) Antibody (Biotin)
20-abx273089
  • EUR 481.00
  • EUR 244.00
  • EUR 1414.00
  • EUR 662.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), APC
4-PAC578Mu01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Biotinylated
4-PAC578Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Cy3
4-PAC578Mu01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), FITC
4-PAC578Mu01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), HRP
4-PAC578Mu01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), PE
4-PAC578Mu01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), APC
4-PAC578Ra01-APC
  • EUR 364.00
  • EUR 3545.00
  • EUR 980.00
  • EUR 467.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Biotinylated
4-PAC578Ra01-Biotin
  • EUR 325.00
  • EUR 2658.00
  • EUR 777.00
  • EUR 400.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Cy3
4-PAC578Ra01-Cy3
  • EUR 444.00
  • EUR 4685.00
  • EUR 1265.00
  • EUR 581.00
  • EUR 261.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), FITC
4-PAC578Ra01-FITC
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), HRP
4-PAC578Ra01-HRP
  • EUR 332.00
  • EUR 3089.00
  • EUR 866.00
  • EUR 421.00
  • EUR 213.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), PE
4-PAC578Ra01-PE
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
Human Pim-1 Oncogene (PIM1) Protein
20-abx068546
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Rat Pim-1 Oncogene (PIM1) Protein
20-abx068547
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Mouse Pim-1 Oncogene (PIM1) Protein
20-abx068548
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat)
4-PAC578Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1)
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), APC-Cy7
4-PAC578Mu01-APC-Cy7
  • EUR 583.00
  • EUR 6610.00
  • EUR 1750.00
  • EUR 778.00
  • EUR 324.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), APC-Cy7
4-PAC578Ra01-APC-Cy7
  • EUR 608.00
  • EUR 6970.00
  • EUR 1840.00
  • EUR 814.00
  • EUR 335.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
Human Pim-1 Oncogene (PIM1)ELISA Kit
201-12-2345 96 tests
EUR 440
  • This Pim-1 Oncogene ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Human Pim-1 Oncogene (PIM1) CLIA Kit
20-abx190030
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Pim-1 Oncogene (PIM1) ELISA Kit
20-abx152744
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Pim-1 Oncogene (PIM1) ELISA Kit
abx573560-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.
Cow Pim-1 Oncogene (PIM1) ELISA Kit
abx519080-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.
Mouse Pim-1 Oncogene (PIM1) ELISA Kit
abx519082-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.
Rat Pim-1 Oncogene (PIM1) ELISA Kit
abx519083-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.
Human Pim-1 Oncogene(PIM1)ELISA Kit
QY-E04698 96T
EUR 361
Rat Pim-1 Oncogene(PIM1)ELISA Kit
QY-E10539 96T
EUR 400
Human Pim-1 Oncogene ELISA Kit (PIM1)
RK02083 96 Tests
EUR 521
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1)CLIA Kit
SCC578Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) CLIA Kit
4-SCC578Hu
  • EUR 5698.00
  • EUR 3061.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Pim-1 Oncogene Clia kit. Alternative names of the recognized antigen: Proto-Oncogene Serine/Threonine-Protein Kinase Pim-1
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Pim-1 Oncogene (PIM1)Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
SEC578Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Pim-1 Oncogene (PIM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Pim-1 Oncogene (PIM1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Pim-1 Oncogene (PIM1) ELISA Kit
4-SEC578Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Pim-1 Oncogene elisa. Alternative names of the recognized antigen: Proto-Oncogene Serine/Threonine-Protein Kinase Pim-1
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Pim-1 Oncogene (PIM1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Mouse Pim-1 Oncogene(PIM1)ELISA Kit
QY-E21184 96T
EUR 361
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), APC
4-PAC578Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), Biotinylated
4-PAC578Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), Cy3
4-PAC578Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), FITC
4-PAC578Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), HRP
4-PAC578Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), PE
4-PAC578Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
ELISA kit for Human PIM1 (Pim-1 Oncogene)
ELK3785 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pim-1 Oncogene (PIM1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Pim-1 Oncoge
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Description: A sandwich ELISA kit for detection of Pim-1 Oncogene from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat), APC-Cy7
4-PAC578Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
Polyclonal PIM1 / Pim-1 Antibody (aa24-37)
APG01139G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PIM1 / Pim-1 (aa24-37). This antibody is tested and proven to work in the following applications:
Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349
Rabbit Pim 1 Oncogene ELISA kit
E04P0753-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Pim 1 Oncogene ELISA kit
E04P0753-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Pim 1 Oncogene ELISA kit
E04P0753-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Pim 1 Oncogene in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Proto-oncogene serine/threonine-protein kinase pim-1(PIM1) ELISA kit
CSB-E11825h-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Proto-oncogene serine/threonine-protein kinase pim-1 (PIM1) in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human Proto-oncogene serine/threonine-protein kinase pim-1(PIM1) ELISA kit
1-CSB-E11825h
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Proto-oncogene serine/threonine-protein kinase pim-1(PIM1) in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx214602
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx125380
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
abx033772-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
abx033772-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx241258
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx327418
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.
Serine/Threonine-Protein Kinase Pim-1 (PIM1) Antibody
20-abx302380
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280
Pim-3 Oncogene (PIM3) Polyclonal Antibody (Human)
4-PAN637Hu01
  • EUR 262.00
  • EUR 2747.00
  • EUR 679.00
  • EUR 331.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM3 (Met1~Leu326)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-3 Oncogene (PIM3)
Pim-2 Oncogene (PIM2) Polyclonal Antibody (Human)
4-PAP797Hu01
  • EUR 262.00
  • EUR 2747.00
  • EUR 679.00
  • EUR 331.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Leu82~Glu291)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Pim-2 Oncogene (PIM2)
Pim-2 Oncogene (PIM2) Polyclonal Antibody (Mouse)
4-PAP797Mu01
  • EUR 266.00
  • EUR 2813.00
  • EUR 694.00
  • EUR 337.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Gly98~Cys319)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-2 Oncogene (PIM2)
Pim-2 Oncogene (PIM2) Polyclonal Antibody (Rat)
4-PAP797Ra01
  • EUR 275.00
  • EUR 2958.00
  • EUR 727.00
  • EUR 350.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PIM2 (Leu34~Glu292)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-2 Oncogene (PIM2)