hicstatistics

Evolution of genomes is reflected in exact DNA

How evolution of genomes is mirrored in actual DNA sequence match statistics. and deletions of DNA sequences, in addition to segmental duplications. These mutational processes can go away distinctive qualitative marks within the statistical options of genomic DNA sequences. One such function is the match size distribution (MLD) of precisely matching sequence segments inside a person genome or…

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hicstatistics

Accurate computation of survival statistics

Correct computation of survival statistics in genome-wide research. A key problem in genomics is to determine genetic variants that distinguish sufferers with totally different survival time following analysis or remedy. Whereas the log-rank check is broadly used for this function, almost all implementations of the log-rank check depend on an asymptotic approximation that isn’t applicable in lots of…

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