hicstatistics

Genetic diversity of circumsporozoite protein in Plasmodium knowlesi isolates from Malaysian Borneo and Peninsular Malaysia

Background: Understanding the genetic variety of candidate genes for malaria vaccines comparable to circumsporozoite protein (csp) might improve the event of vaccines for treating Plasmodium knowlesi. Therefore, the goal of this examine is to research the genetic variety of non-repeat areas of csp in P. knowlesi from Malaysian Borneo and Peninsular Malaysia.   Strategies: A complete of…

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hicstatistics

A compound heterozygous mutation of the alkaline phosphatase ALPL gene causes hypophosphatasia in a Han Chinese family

Hypophosphatasia (HPP) is a uncommon hereditary systemic illness that’s characterised by faulty bone and/or dental mineralization, and is brought on by mutations within the alkaline phosphatase gene (ALPL). The current examine investigated the ALPL mutation in a Chinese language Han household with HPP and studied the pathogenesis of the mutations of the ALPL gene. DNA…

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