hicstatistics

Accurate computation of survival statistics

Correct computation of survival statistics in genome-wide research. A key problem in genomics is to determine genetic variants that distinguish sufferers with totally different survival time following analysis or remedy. Whereas the log-rank check is broadly used for this function, almost all implementations of the log-rank check depend on an asymptotic approximation that isn’t applicable in lots of…

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hicstatistics

A computational Approach Using Ratio Statistics

A Computational Method Utilizing Ratio Statistics for Figuring out Housekeeping Genes from cDNA Microarray Knowledge. We predict housekeeping genes from replicate microarray gene expression information of human lymphoblastoid cells and liver tissue with outliers eliminated utilizing a scoring scheme, by an algorithm based mostly on statistical speculation testing, assuming that such genes are constitutively expressed. Just a few predicted…

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hicstatistics

Expression profiling and functional verification of flavonoid 3′-hydroxylase gene from leaves of Euryale ferox

Leaves of Euryale ferox are wealthy in anthocyanins. Anthocyanin synthesis is without doubt one of the essential branches of the flavonoid synthesis pathway, through which flavonoid 3′-hydroxylase(F3’H) can take part within the formation of essential intermediate merchandise of anthocyanin synthesis. In response to the information of E. ferox transcriptome, F3’H cDNA sequence was cloned within…

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