hicstatistics

Fold change rank ordering statistics

Fold change rank ordering statistics: a brand new methodology for detecting differentially expressed genes. BACKGROUND Completely different strategies have been proposed for analyzing differentially expressed (DE) genes in microarray information. Strategies primarily based on statistical assessments that incorporate expression stage variability are used extra generally than these primarily based on fold change (FC). Nevertheless, FC primarily based…

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hicstatistics

Accurate computation of survival statistics

Correct computation of survival statistics in genome-wide research. A key problem in genomics is to determine genetic variants that distinguish sufferers with totally different survival time following analysis or remedy. Whereas the log-rank check is broadly used for this function, almost all implementations of the log-rank check depend on an asymptotic approximation that isn’t applicable in lots of…

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hicstatistics

A computational Approach Using Ratio Statistics

A Computational Method Utilizing Ratio Statistics for Figuring out Housekeeping Genes from cDNA Microarray Knowledge. We predict housekeeping genes from replicate microarray gene expression information of human lymphoblastoid cells and liver tissue with outliers eliminated utilizing a scoring scheme, by an algorithm based mostly on statistical speculation testing, assuming that such genes are constitutively expressed. Just a few predicted…

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hicstatistics

Comparison of adaptive multiple phenotype association tests

Comparability of adaptive a number of phenotype affiliation checks utilizing abstract statistics in genome-wide affiliation research Genome-wide affiliation research have been profitable mapping loci for particular person phenotypes, however few research have comprehensively interrogated proof of shared genetic results throughout a number of phenotypes concurrently. Statistical strategies have been proposed for analyzing a number of phenotypes utilizing abstract…

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